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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16947 |
SU16f
3-substituted indolin-2-one 16f,SU-16F,SU 16F |
PDGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
SU16f (3-substituted indolin-2-one 16f) 是一种有效的,选择性 PDGFRβ 抑制剂,对 PDGFRβ,PDGFR1,PDGFR2 的 IC50 分别为 10 nM,140 nM,2.29 μM。SU16f 抑制 PDGFRβ 受体从而可以阻断胃癌来源的间充质干细胞 (GC-MSC) 条件培养基在胃癌细胞增殖和迁移中的促进作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01050 |
PDGF R beta/CD140b Protein, Canine, Recombinant (His)
JTK12,PDGF R β,PDGFR-β,PDGFR,... |
Canine | HEK293 |
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and re... | |||
TMPY-05497 |
PDGFRB Protein, Human, Recombinant (hFc)
PDGFR,CD140B,PENTT,JTK12,KOGS,pla... |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... | |||
TMPK-00422 |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
PDGFR-2,PDGF R β/CD140b,PDGFR... |
Human | HEK293 |
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and re... | |||
TMPK-00421 |
PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)
PDGFR1,CD140B,PDGFR-2,PD... |
Human | HEK293 |
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and re... | |||
TMPY-01207 |
PDGFRB Protein, Human, Recombinant (His)
CD140B,IMF1,KOGS,PDGFR,PDGFR<... |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... | |||
TMPY-04937 |
PDGFRB Protein, Human, Recombinant (His), Biotinylated
platelet-derived growth factor receptor, beta polypeptide,CD... |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... | |||
TMPY-05358 |
PDGFRB Protein, Human, Recombinant
PENTT,platelet-derived growth factor receptor, beta polypept... |
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d... |