6
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27122 |
Dasantafil
SCH446132,SCH-446132,SCH 446132 |
PDE | Metabolism |
Dasantafil (SCH446132) 是一种小分子磷酸二酯酶-5A(PDE5A)抑制剂,可用于治疗泌尿生殖系统疾病和研究勃起功能障碍。 | |||
T15381 |
Gisadenafil
UK-369003,吉沙那非 |
PDE | Metabolism |
Gisadenafil (UK-369003) 是一种特异性磷酸二酯酶 5 (PDE5) 抑制剂,IC50 为 3.6 nM,可防止 cGMP 降解。 | |||
T27720 |
KD-027
KD 027,SLx-2101,SLx2101,KD027,SLx 2101 |
||
KD-027, a PDE5A inhibitor, is used potentially for the treatment of hypertension. | |||
T29048 |
UK 357903
UK357903,UK-357903 |
||
UK 357903, a phosphodiesterase 5A (PDE5A) inhibitor, is used potentially for the treatment of erectile dysfunction. | |||
T28296 |
Parogrelil hydrochloride
INDI-702,NM-702,NT-702,NM702,INDI702 |
||
Parogrelil is a phosphodiesterase (PDE3/PDE5A) inhibitor potentially for the treatment of intermittent. Parogrelil suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. Parogrelil improves reduced walking | |||
T11400 |
Gisadenafil besylate
UK 369003-26 |
Others | Others |
Gisadenafil besylate (UK 369003-26) is a specific, orally active phosphodiesterase 5 (PDE5) inhibitor ,prevents degradation of cyclic guanosine monophosphate (cGMP), with an IC50 of 3.6 nM . |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN2159 |
Robustine
大叶桉亭,8-羟基白鲜碱,4-甲氧基呋喃并[2,3-B]喹啉-8-醇 |
PDE | Metabolism |
Robustine 是一种从 Dictamnus albus 获得的呋喃喹啉生物碱,在体外对人磷酸二酯酶 5 (hPDE5A) 具有抑制作用。 | |||
T38108 |
Fulvic Acid
|
Antioxidant; PDE | Metabolism; oxidation-reduction |
Fulvic Acid 是一种来自土壤、沉积物或水生环境中微生物产生的腐殖质的天然产物,是一种首次青霉菌中分离出的酚酸和真菌代谢产物。Fulvic Acid 抑制淀粉样蛋白b (17-42) (AB17-42)二聚化,破坏预先形成的AB17-42三聚体,并结合到磷酸二酯酶5A (PDE5A)的催化位点,可以调节机体免疫系统,影响细胞的氧化状态,改善胃肠功能。Fulvic Acid 可作为氧化剂或还原剂, 具有研究糖尿病等慢性炎症性疾病的潜力。 |