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Targets Recommended: Others

4

抑制剂 & 化合物

12

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T24494 MP265

S-(4-氯苄基)氯化异硫脲,MP-265,MP 265

Others Others
MP265 破坏 MreB 细胞骨架并具有抗增殖作用。
T1857 TMP269

HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair
TMP269 是一种有效的特异性 IIa 类 HDAC 抑制剂,分别抑制 HDAC 4/HDAC 5/HDAC 7/HDAC 9,IC50值分别为 157 nM,97 nM,43 nM 和 23 nM。
T69186 CP26

CP26 is a novel inhibitor of ER-to-cytosol protein dislocation, exhibiting anti-dengue and anti-Zika virus activity.
T82684 Connexin mimetic peptide 40,37GAP26

Connexin mimetic peptide 40,37GAP26是一种生物活性肽,对应Cx37和Cx40主要血管连接蛋白的胞外环GAP26结构域,命名基于Cx同源性为37,40Gap26。本化合物主要用于研究间隙连接对环吡嗪酸(CPA)通过啮齿动物髂动脉壁导致的内皮超极化扩散的影响。Cx37和Cx40形成的间隙连接斑块在内皮细胞中高度丰富,而Connexin mimetic peptide 40,37GAP26能抑制内膜下超极化。

化合物

MP265
Cat.No: T24494
Synonym: S-(4-氯苄基)氯化异硫脲,MP-265,MP 265
Target: Others
TMP269
Cat.No: T1857
Synonym:
Target: HDAC
CP26
Cat.No: T69186
Synonym:
Target:
Connexin mimetic peptide 40,37GAP26
Cat.No: T82684
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPK-01278 CD69 Protein, Cynomolgus, Recombinant (His)

CLEC2C,AIM,EA1,MLR-3,GP32,BL-AC,BL-AC/P26,P26

Cynomolgus HEK293 Cells
CLEC2C (CD69) is a membrane-bound, type II C-lectin receptor and acts as a costimulatory molecule for T cell activation and proliferation. It is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. CLEC2C is a disulfide-linked homodimer protein with two differentially glycosylated subunits.
TMPY-01234 CD69 Protein, Human, Recombinant (His)

BL-AC/P26,CLEC2C,GP32/28,AIM,CD69 molecule,MLR-3,EA...

Human HEK293 Cells
CD69 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is Q07108.
TMPY-06159 SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.5 kDa and the accession number is A0A6G7K2L4.
TMPH-01183 CYP26B1 Protein, Human, Recombinant (His)

Cytochrome P450 26A2,CYP26B1,P450RAI2,Cytochrome P4...

Human E. coli
CYP26B1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 63.5 kDa and the accession number is Q9NR63.
TMPY-06131 SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.4 kDa and the accession number is A0A6G7K2L4.
TMPY-06268 SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His & Avi), Biotinylated

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 78.28 kDa and the accession number is A0A6G7K2L4.
TMPH-01251 DUSP26 Protein, Human, Recombinant (His & SUMO)

MKP-8,NATA1,DSP-4,SKRP3,DUSP26,MKP8,LDP-4,LDP4,DUSP...

Human E. coli
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
TMPY-06429 SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His)

SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 133.72 kDa and the accession number is A0A6G7K2L4.
TMPY-06136 SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.5 kDa and the accession number is A0A6G7K2L4.
TMPY-06420 SARS-CoV-2 Spike S1 Protein (P26S & 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H, His)

SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (P26S & 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 75.77 kDa and the accession number is A0A6G7K2L4.
TMPY-06682 PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His)

hPD-1,hSLE1,hPD-l,CD279,PD1,PD-1,programmed cell death 1,SLE...

Human HEK293 Cells
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.65 kDa and the accession number is NP_005009.2.
TMPH-02284 USP26 Protein, Human, Recombinant (His)

Human E. coli
Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway.

重组蛋白

CD69 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01278
Species: Cynomolgus
Expression System: HEK293 Cells
CD69 Protein, Human, Recombinant (His)
Cat.No: TMPY-01234
Species: Human
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His)
Cat.No: TMPY-06159
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
CYP26B1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01183
Species: Human
Expression System: E. coli
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His)
Cat.No: TMPY-06131
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His & Avi), Biotinylated
Cat.No: TMPY-06268
Species: SARS-CoV-2
Expression System: HEK293 Cells
DUSP26 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01251
Species: Human
Expression System: E. coli
SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His)
Cat.No: TMPY-06429
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His)
Cat.No: TMPY-06136
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1 Protein (P26S & 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H, His)
Cat.No: TMPY-06420
Species: SARS-CoV-2
Expression System: HEK293 Cells
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His)
Cat.No: TMPY-06682
Species: Human
Expression System: HEK293 Cells
USP26 Protein, Human, Recombinant (His)
Cat.No: TMPH-02284
Species: Human
Expression System: E. coli
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