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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T61688 Nrf2 activator-2

Nrf2 activator-2 (referred to as compound O15), an Osthole derivative, is a highly potent Nrf2 agonist exhibiting an EC 50 of 2.9 μM in 293 T cells. By effectively disrupting the binding between Keap1 and Nrf2, Nrf2 activator-2 activates the Nrf2 pathway. Furthermore, this compound significantly reduces the ubiquitination of Nrf2 in cells, indicating its potential in regulating Nrf2 activity [1].

化合物

Nrf2 activator-2
Cat.No: T61688
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2848 Osthole

Osthol,NSC 31868,蛇床子素,Ostol

Apoptosis; HBV; Parasite; Histamine Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Osthole (Osthol) 是一种天然抗组胺药替代试剂,可刺激成骨细胞增殖和分化。它可抑制组胺 H1受体活性,还可抑制细胞培养物中 HBV 的分泌。

天然产物

Osthole
Cat.No: T2848
Synonym: Osthol,NSC 31868,蛇床子素,Ostol
Target: Apoptosis, HBV, Parasite, Histamine Receptor
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