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Targets Recommended: Glucagon Receptor

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T78097L	Mazdutide acetate（2259884-03-0 free base） Mazdutide acetate（2259884-03-0 free base）,OXM-3 acetate,LY-3305677 acetate,IBI-362 acetate	Glucagon Receptor	GPCR/G Protein
	Mazdutide acetate 是一种高效的胰高血糖素样肽 (GLP-1R) 与胰高血糖素受体 (GCGR) 的共激动剂，是一种胃泌酸调节素类似物。Mazdutide acetate可刺激小鼠胰岛的胰岛素分泌，可用于研究肥胖和 2 型糖尿病 (T2D) 。
T78097	Mazdutide IBI-362,LY-3305677,OXM-3
	Mazdutide (IBI-362; LY-3305677) 是一种具有安全性和耐受性的胃泌酸调节素类似物，用于肥胖和2型糖尿病(T2D)的研究。它同时作为胰高血糖素样肽(GLP-1R)和胰高血糖素受体(GCGR)的共激动剂，表现出长效作用。
T80079	Mazdutide TFA LY-3305677 TFA,IBI-362 TFA,OXM-3 TFA
	Mazdutide (IBI-362; LY-3305677) TFA 是一款GLP-1R与GCGR的共激动剂，同时是长效合成胃泌酸调节素类似物。该化合物安全性和耐受性良好，适用于肥胖与T2D研究。
T68122L	Oxmetidine FA Oxmetidine FA(72830-39-8 Free base)	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Oxmetidine FA 是一种可口服的特异性组胺 H2 受体拮抗剂，具有抗溃疡作用。
T68122	Oxmetidine SKF 92994,Oxmetidina,Oxmetidinum	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Oxmetidine (SKF 92994) 是一种新型 H2 受体拮抗剂，具有细胞毒性。 Oxmetidine 抑制心脏和血管组织中跨膜钙通量,可用于治疗活动性十二指肠溃疡。
T68587	Oxmetidine mesylate
	Oxmetidine mesylate is an antagonist to Histamine H2 Receptors
T68966	Oxmetidine HCl
	Oxmetidine HCl is an antagonist to Histamine H2 Receptors
T82374	FOXM1-IN-2
	FOXM1-IN-2是抗肿瘤活性的FOXM1抑制剂。
T73172	FOXM1-IN-1
	FOXM1-IN-1 是一种有效的 FOXM1抑制剂，IC50值为 2.65 µM。FOXM1-IN-1 显示出抗增殖活性。FOXM1-IN-1 降低FOXM1、PLK1、CDC25B 蛋白的表达。

化合物

Mazdutide acetate（2259884-03-0 free base）

Cat.No: T78097L

Synonym: Mazdutide acetate（2259884-03-0 free base）,OXM-3 acetate,LY-3305677 acetate,IBI-362 acetate

Target: Glucagon Receptor

Mazdutide

Cat.No: T78097

Synonym: IBI-362,LY-3305677,OXM-3

Target:

Mazdutide TFA

Cat.No: T80079

Synonym: LY-3305677 TFA,IBI-362 TFA,OXM-3 TFA

Target:

Oxmetidine FA

Cat.No: T68122L

Synonym: Oxmetidine FA(72830-39-8 Free base)

Target: Histamine Receptor

Oxmetidine

Cat.No: T68122

Synonym: SKF 92994,Oxmetidina,Oxmetidinum

Target: Histamine Receptor

Oxmetidine mesylate

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00742	GCG Protein, Human, Recombinant (His) Glicentin,GRPP,GLP-2,Glucagon-Like Peptide 1,OXM,Gl...	Human	HEK293 Cells
	Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin....
TMPH-01351	FOxM1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. FOxM1 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is Q08050.
TMPH-01350	FOxM1 Protein, Human, Recombinant (GST)	Human	E. coli
	Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. FOxM1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 43.8 kDa and the accession number is Q08050.