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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76975 |
Tomaralimab
OPN-305 |
TLR | Immunology/Inflammation |
Tomaralimab (OPN-305) 是一种人源化的靶向 TLR2 的 IgG4 单克隆抗体。Tomaralimab 可用于研究骨髓增生异常综合征 (MDS) 。 | |||
T62820 | OPN expression inhibitor 1 | ||
OPN expression inhibitor 1 (Compound 11),一种针对骨钙素 (osteopontin (OPN)) 表达的抑制剂,适用于乳腺癌研究。 | |||
T40292 |
Opnurasib
NVP-JDQ443,JDQ-443,Opnurasib |
Ras | GPCR/G Protein; MAPK |
Opnurasib (JDQ-443) 是一种可口服且具有选择性和有效性的共价 KRAS G12C 抑制剂,具有抗肿瘤活性,可用于研究晚期非小细胞肺癌。 | |||
T26456 |
A 83586C
A83586C,A-83586C |
||
A-83586C is a depsipeptide antibiotic from Streptomyces karnatakensis with potent against Gram-positive activity in vitro. A-83586C acts as a highly potent inhibitor of beta-catenin/TCF4 signaling within cancer cells, while simultaneously downregulating o |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06988 |
Osteopontin Protein, Human, Recombinant (aa 17-166, His)
BNSP,ETA-1,OPN,BSPI |
Human | HEK293 Cells |
Osteopontin Protein, Human, Recombinant (aa 17-166, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.64 kDa. and the accession number is P10451. | |||
TMPY-01288 |
Osteopontin Protein, Human, Recombinant (His)
OPN,BSPI,BNSP,ETA-1,secreted phosphoprotein 1 |
Human | HEK293 Cells |
Osteopontin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDE2. | |||
TMPK-00676 |
Osteopontin Protein, Human, Recombinant (aa 17-300, His)
BSP-1,Nephropontin,BNSP,ETA-1,OPN,Bone sialoprotein... |
Human | HEK293 Cells |
Osteopontin Protein, Human, Recombinant (aa 17-300, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.8 kDa and the accession number is A0A024RDE6. | |||
TMPK-00807 |
Osteopontin Protein, Mouse, Recombinant (His)
ETA-1,SPP1,OPN,Bone sialoprotein 1,BNSP,SPP-1,Osteo... |
Mouse | HEK293 Cells |
Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration and apoptosis were assessed by Transwell migration assays and flow cytometric analysis, respectively. SPP1 is highly expressed in tumor tissues and TAMs isolated from patients with an advanced TNM stage, and also in PMA-treated THP-1 cells. | |||
TMPK-00538 |
Osteopontin Protein, Cynomolgus, Recombinant (His)
BSP-1,BNSP,SPP1,Nephropontin,OPN,Bone sialoprotein ... |
Cynomolgus | HEK293 Cells |
Osteopontin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 33.16 kDa and the accession number is A0A2K5WL90. | |||
TMPH-03332 |
OPN4 Protein, Rat, Recombinant (His)
|
Rat | E. coli |
Photoreceptor that binds cis-retinaldehydes. Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light. May be involved in the optokinetic visual tracking response. May be involved in the regulation of retinal hyaloid vessel growth and regression. OPN4 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 53.9 kDa and the accession number is Q8R456. | |||
TMPH-01615 |
OPN1LW Protein, Human, Recombinant (His)
|
Human | E. coli |
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. OPN1LW Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.4 kDa and the accession number is P04000. | |||
TMPK-01028 |
BSPII Protein, Mouse, Recombinant (His)
IBSP,SP II,BSP,BSP II,BNSP,BSP-II,BSP 2,SPII,SP-II |
Mouse | HEK293 Cells |
Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and progression. Here, we report on the selection of antisense oligonucleotides (ASOs), which are effective in reducing their protein levels. |