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Targets Recommended: TLR

4

抑制剂 & 化合物

8

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76975 Tomaralimab

OPN-305

TLR Immunology/Inflammation
Tomaralimab (OPN-305) 是一种人源化的靶向 TLR2 的 IgG4 单克隆抗体。Tomaralimab 可用于研究骨髓增生异常综合征 (MDS) 。
T62820 OPN expression inhibitor 1

OPN expression inhibitor 1 (Compound 11),一种针对骨钙素 (osteopontin (OPN)) 表达的抑制剂,适用于乳腺癌研究。
T40292 Opnurasib

NVP-JDQ443,JDQ-443,Opnurasib

Ras GPCR/G Protein; MAPK
Opnurasib (JDQ-443) 是一种可口服且具有选择性和有效性的共价 KRAS G12C 抑制剂,具有抗肿瘤活性,可用于研究晚期非小细胞肺癌。
T26456 A 83586C

A83586C,A-83586C

A-83586C is a depsipeptide antibiotic from Streptomyces karnatakensis with potent against Gram-positive activity in vitro. A-83586C acts as a highly potent inhibitor of beta-catenin/TCF4 signaling within cancer cells, while simultaneously downregulating o

化合物

Tomaralimab
Cat.No: T76975
Synonym: OPN-305
Target: TLR
OPN expression inhibitor 1
Cat.No: T62820
Synonym:
Target:
Opnurasib
Cat.No: T40292
Synonym: NVP-JDQ443,JDQ-443,Opnurasib
Target: Ras
A 83586C
Cat.No: T26456
Synonym: A83586C,A-83586C
Target:
Cat. No. Product Name Species Expression System
TMPY-06988 Osteopontin Protein, Human, Recombinant (aa 17-166, His)

BNSP,ETA-1,OPN,BSPI

Human HEK293 Cells
Osteopontin Protein, Human, Recombinant (aa 17-166, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.64 kDa. and the accession number is P10451.
TMPY-01288 Osteopontin Protein, Human, Recombinant (His)

OPN,BSPI,BNSP,ETA-1,secreted phosphoprotein 1

Human HEK293 Cells
Osteopontin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDE2.
TMPK-00676 Osteopontin Protein, Human, Recombinant (aa 17-300, His)

BSP-1,Nephropontin,BNSP,ETA-1,OPN,Bone sialoprotein...

Human HEK293 Cells
Osteopontin Protein, Human, Recombinant (aa 17-300, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.8 kDa and the accession number is A0A024RDE6.
TMPK-00807 Osteopontin Protein, Mouse, Recombinant (His)

ETA-1,SPP1,OPN,Bone sialoprotein 1,BNSP,SPP-1,Osteo...

Mouse HEK293 Cells
Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration and apoptosis were assessed by Transwell migration assays and flow cytometric analysis, respectively. SPP1 is highly expressed in tumor tissues and TAMs isolated from patients with an advanced TNM stage, and also in PMA-treated THP-1 cells.
TMPK-00538 Osteopontin Protein, Cynomolgus, Recombinant (His)

BSP-1,BNSP,SPP1,Nephropontin,OPN,Bone sialoprotein ...

Cynomolgus HEK293 Cells
Osteopontin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 33.16 kDa and the accession number is A0A2K5WL90.
TMPH-03332 OPN4 Protein, Rat, Recombinant (His)

Rat E. coli
Photoreceptor that binds cis-retinaldehydes. Contributes to pupillar reflex, photoentrainment and other non-image forming responses to light. May be involved in the optokinetic visual tracking response. May be involved in the regulation of retinal hyaloid vessel growth and regression. OPN4 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 53.9 kDa and the accession number is Q8R456.
TMPH-01615 OPN1LW Protein, Human, Recombinant (His)

Human E. coli
Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. OPN1LW Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.4 kDa and the accession number is P04000.
TMPK-01028 BSPII Protein, Mouse, Recombinant (His)

IBSP,SP II,BSP,BSP II,BNSP,BSP-II,BSP 2,SPII,SP-II

Mouse HEK293 Cells
Osteopontin (OPN), bone sialoprotein (BSPII), and osteonectin (ON) belong to a family of glycoproteins, which have been linked to cancer metastasis and progression. Here, we report on the selection of antisense oligonucleotides (ASOs), which are effective in reducing their protein levels.

重组蛋白

Osteopontin Protein, Human, Recombinant (aa 17-166, His)
Cat.No: TMPY-06988
Species: Human
Expression System: HEK293 Cells
Osteopontin Protein, Human, Recombinant (His)
Cat.No: TMPY-01288
Species: Human
Expression System: HEK293 Cells
Osteopontin Protein, Human, Recombinant (aa 17-300, His)
Cat.No: TMPK-00676
Species: Human
Expression System: HEK293 Cells
Osteopontin Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00807
Species: Mouse
Expression System: HEK293 Cells
Osteopontin Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00538
Species: Cynomolgus
Expression System: HEK293 Cells
OPN4 Protein, Rat, Recombinant (His)
Cat.No: TMPH-03332
Species: Rat
Expression System: E. coli
OPN1LW Protein, Human, Recombinant (His)
Cat.No: TMPH-01615
Species: Human
Expression System: E. coli
BSPII Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01028
Species: Mouse
Expression System: HEK293 Cells
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