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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T2096	Framycetin sulfate Neomycin Sulphate B,硫酸新霉素B,Framycetin sulphate	Antibacterial; Antibiotic	Microbiology/Virology
	Framycetin sulfate (Neomycin Sulphate B) 是一种氨基糖苷类抗生素，是 RNase P 裂解活性抑制剂，Ki 为 35 μM。它抑制锤头状核酶，Ki 值为 13.5 μM，可用于肝性脑病和肠致病性大肠杆菌感染的研究。
T70752	Neomycin (free base)
	Neomycin (free base) is an antibiotic complex produced by Streptomyces fradiae. It is composed of neomycins A, B, and C. It acts by inhibiting translation during protein synthesis.
T73953	Neomycin C
	Neomycin C是新霉素复合物中的两个主要活性异构体之一，为含2-DOS的氨基糖苷复合物，包括neomycin A，neomycin B以及neomycin C。其活性仅为Neomycin B的一半。
T15348	Framycetin Fradiomycin B,新霉素B,Neomycin B	Others	Others
	Framycetin is an aminoglycoside antibiotic and it also inhibits hammerhead ribozyme (Ki: 13.5 μM).
T75667	Neamine
	Neamine，新霉素降解产物，为广谱氨基糖苷类抗生素。作为抗血管生成剂，针对血管生成素 (angiogenin)，展现抗菌、抗肿瘤及神经保护活性。
T13658	DMEA-PNU-159682	Others	Others
	DMEA-PNU-159682 (molecule D12) is an ADC cytotoxin molecule, including neomycin (MMDX) metabolites from liver microsomes and effective ADC cytotoxin PNU-159682.
T36182	Neamine tetrahydrochloride
	Neamine tetrahydrochloride 是一种广谱氨基糖苷类抗生素，一种新霉素的降解产物。Neamine tetrahydrochloride 可通过靶向血管生成素 (angiogenin) 发挥抗血管生成作用。Neamine tetrahydrochloride 具有抗菌，抗肿瘤和神经保护活性。
T65387	Paromomycin, sulfate (1:1)
	Paromomycin (Sulfate Salt) is an aminoglycoside that is active against Gram-negative and many Gram-positive bacteria as well as some protozoa and cestodes. Paromomycin in combination with sodium stibogluconate has proven to be effective in African and Indian VL (visceral leishmaniasis) and improves survival in African VL[3]. PS (Paromomycin Sulfate) is effective for elimination of B. coli without hematological side effects[4]. The activity of phosphoglucose isomerase was slightly inhibited by 10...

化合物

Framycetin sulfate

Cat.No: T2096

Synonym: Neomycin Sulphate B,硫酸新霉素B,Framycetin sulphate

Target: Antibacterial, Antibiotic

Neomycin (free base)

Synonym: Fradiomycin B,新霉素B,Neomycin B

Neamine tetrahydrochloride

Cat.No: T36182

Synonym:

Target:

Paromomycin, sulfate (1:1)

Cat.No: T65387

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T0950	Neomycin sulfate Framycin sulfate,硫酸新霉素	Phospholipase; ribosome; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology
	Neomycin sulfate (Framycin sulfate) 是一种广谱的氨基糖苷类抗生素。Neomycin sulfate 可以阻断细菌蛋白质的合成以发挥抗菌活性。Neomycin sulfate 常用于筛选具有 Neo 抗性基因的原核和真核细胞。
T1104	Paromomycin Sulfate Aminosidine sulfate,Paromomycin sulfate salt,硫酸巴龙霉素,巴龙霉素硫酸盐	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Paromomycin Sulfate (Aminosidine sulfate) 是一种广谱氨基糖苷类抗生素，是具有杀螨杀菌作用的新霉素衍生物。它通过与细菌 30S 核糖体 A 位点的 RNA 寡核苷酸特异性结合，使 mRNA 的翻译提前终止，并抑制蛋白质合成。它可研究细菌和寄生虫感染。

天然产物

Neomycin sulfate

Cat.No: T0950

Synonym: Framycin sulfate,硫酸新霉素

Target: Phospholipase, ribosome, Antibacterial, Antibiotic

Paromomycin Sulfate

Cat.No: T1104

Synonym: Aminosidine sulfate,Paromomycin sulfate salt,硫酸巴龙霉素,巴龙霉素硫酸盐

Target: Antibacterial, Antibiotic, Parasite

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