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Cat. No. Product Name Target Signaling Pathways
T1258 Nabumetone

BRL14777,萘丁美酮

COX; Glutathione Peroxidase Immunology/Inflammation; Metabolism; Neuroscience
Nabumetone (BRL14777) 是一种非甾体抗炎药,是选择性COX-2抑制剂,其活性代谢物 6MNA 可抑制环加氧酶 I 和 II。
T68919 Nabumetone Alcohol

Nabumetone alcohol is the alcohol form of nabumetone, a non-steroidal anti-inflammatory drug (NSAID) that is rapidly metabolized in the liver to a major active metabolite, 6-methoxy-2-naphthyl acetic acid, which inhibits the cyclooxygenase enzyme and preferentially blocks COX-2 activity (which is indirectly responsible for the production of inflammation and pain during arthritis).
T0663 2-Bromo-6-methoxynaphthalene

5-HT Receptor GPCR/G Protein; Neuroscience
2-Bromo-6-methoxynaphthalene 用于通过 Heck 反应合成 nabumetone [4-(6-methoxy-2-naphthalenyl)-2-butanone]。

化合物

Nabumetone
Cat.No: T1258
Synonym: BRL14777,萘丁美酮
Target: COX, Glutathione Peroxidase
Nabumetone Alcohol
Cat.No: T68919
Synonym:
Target:
2-Bromo-6-methoxynaphthalene
Cat.No: T0663
Synonym:
Target: 5-HT Receptor
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