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Cat. No. | Product Name | Target | Signaling Pathways |
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T11154 | EG01377 | Others | Others |
EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 μM for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP2. | |||
T72276 |
EG01377 dihydrochloride
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EG01377 dihydrochloride 是有效的、可生物利用的和选择性的neuropilin-1 (NRP1)抑制剂,Kd 值为 1.32 μM,对NRP1-a1和NRP1-b1的IC50值均为 609 nM。EG01377 dihydrochloride 具有抗血管生成,抗迁移及抗肿瘤等活性。 | |||
T11154L |
EG01377 2HCl
EG01377 2HCl(2227996-00-9 Free base) |
Complement System | Immunology/Inflammation |
EG01377 2HCl 是一种有效的、可生物利用的和选择性的neuropilin-1(NRP1)抑制剂,Kd 值为1.32μM,EG01377 2HCl 对NRP1-a1和NRP1-b1的IC50值均为609nM。EG01377具有抗血管生成,抗迁移及抗肿瘤等活性。 |
Cat. No. | Product Name | Species | Expression System |
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TMPY-02682 |
NELL2 Protein, Human, Recombinant (His)
NEL-like 2 (chicken),NRP2 |
Human | Baculovirus Insect Cells |
A brain-enriched secreting signal peptide, NELL2, has been suggested to play multiple roles in the development, survival, and activity of neurons in the mammal. NELL2 is an abundant glycoprotein containing an EGF-like domain in the neural tissues where it has multiple physiological functions by interacting with protein kinase C (PKC). There are two different splicing variant forms of NELL2 identified so far. One is secreted NELL2 (sNELL2) which is a neuron-specific variant and the other is cytos... | |||
TMPH-01194 |
Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO)
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HHV-5 | E. coli |
Plays a role in viral entry into host cells. Forms a pentameric complex at the surface of the viral envelope together with gH, gL, UL130 and UL131. This complex is required for entry in epithelial, endothelial and myeloid host cells. Mechanistically, engages host receptor(s) including neurophilin 2/NRP2 to mediate infection. Human cytomegalovirus (HCMV) (strain AD169) UL130 Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.... |