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Search Results for " nrp1 "

6

抑制剂 & 化合物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T62727	NRP1 antagonist 1
	NRP1 antagonist 1 (compound 12a) 是一种 NRP1 的有效拮抗剂 (IC50: 19.1 μM)。NRP1 antagonist 1 具有潜力进行癌症研究的研究。
T62845	NRP1 antagonist 2
	NRP1 antagonist 2 (Compound 1) 是一种 NRP1 拮抗剂。
T11154L	EG01377 2HCl EG01377 2HCl(2227996-00-9 Free base)	Complement System	Immunology/Inflammation
	EG01377 2HCl 是一种有效的、可生物利用的和选择性的neuropilin-1(NRP1)抑制剂，Kd 值为1.32μM，EG01377 2HCl 对NRP1-a1和NRP1-b1的IC50值均为609nM。EG01377具有抗血管生成，抗迁移及抗肿瘤等活性。
T11153	EG00229	Others	Others
	EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2. EG00229 is a neuropilin 1 (NRP1) receptor antagonist.
T11154	EG01377	Others	Others
	EG01377 has antiangiogenic, antimigratory, and antitumor effects.EG01377 is a neuropilin-1 (NRP1) antagonist, with a Kd of 1.32 μM for NRP1-b1, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1, but shows no effect on NRP2.
T72276	EG01377 dihydrochloride
	EG01377 dihydrochloride 是有效的、可生物利用的和选择性的neuropilin-1 (NRP1)抑制剂，Kd 值为 1.32 μM，对NRP1-a1和NRP1-b1的IC50值均为 609 nM。EG01377 dihydrochloride 具有抗血管生成，抗迁移及抗肿瘤等活性。

化合物

NRP1 antagonist 1

Cat.No: T62727

NRP1 antagonist 2

Cat.No: T62845

Cat.No: T11154L

Synonym: EG01377 2HCl(2227996-00-9 Free base)

Target: Complement System

Cat.No: T11153

Target: Others

Cat.No: T11154

Target: Others

EG01377 dihydrochloride

Cat.No: T72276

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00355	Neuropilin-1 Protein, Human, Recombinant (aa 22-644, Avi & His), Biotinylated CD304,VEGF165R,NRP1,NRPN...	Human	HEK293 Cells
	Neuropilin-1 (Npn-1, previously neuropilin; also CD304) is a 130 - 140 kDa type I transmembrane (TM) glycoprotein that regulates axon guidance and angiogenesis. Two homologues, Neuropilin-1 and Neuropilin-2, are identified. Neuropilin-1 binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds ...
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His) VEGFA,VEGF-A,Vascular permeability factor,VPF,血管内皮生长因子,Vascu...	Human	HEK293 Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel...

重组蛋白

Neuropilin-1 Protein, Human, Recombinant (aa 22-644, Avi & His), Biotinylated

Cat.No: TMPJ-00355

Species: Human

Expression System: HEK293 Cells

VEGF121 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00865

Species: Human

Expression System: HEK293 Cells

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