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Search Results for " ngr "

Targets Recommended: Others

8

抑制剂 & 化合物

1

化合物库

17

重组蛋白

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Cat. No.	Product Name
L9900	药用辅料化合物库		182 compounds
	182 种 FDA 批准药品中的非活性成分集合

化合物库

药用辅料化合物库

Cat.No: L9900

Compounds: 182

Cat. No.	Product Name	Target	Signaling Pathways
TP2185	NGR peptide	Others	Others
	Cell-penetrating peptide
TP1771	NGR peptide Trifluoroacetate
	NGR peptide Trifluoroacetate containing the asparagine-glycine-arginine (NGR) motif is recognized by CD13/aminopeptidase N (APN) receptor isoforms that are selectively overexpressed in tumor neovasculature.
T76568	Aminopeptidase N Ligand (CD13) NGR peptide
	AminopeptidaseN Ligand (CD13) NGR peptide 是靶向CD13的多肽，常见于癌症研究中，用作细胞内传递的载体介质。
T5036	cangrelor tetrasodium	GPR; P2Y Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Cangrelor tetrasodium 是三磷酸腺苷类似物，是可逆的选择性血小板P2Y12拮抗剂，也是非特异性的GPR17拮抗剂。它直接阻断腺苷二磷酸诱导的血小板活化和聚集，具有迅速有效的抗血小板作用。
T70335	Cangrelor free acid
	Cangrelor is a P2Y12 inhibitor, and was approved in June 2015 as an antiplatelet drug for intravenous application. Cangrelor is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. It does not require metabolic conversion to an active metabolite. This allows cangrelor’s immediate effect after infusion, and the therapeutic effects can be maintained with...
T81685	NEP(1-40) TFA
	NEP(1-40) TFA 是一种Nogo-66 受体 (NgR) 的肽类拮抗剂，其作用机制为通过抑制髓蛋白所引发的损伤逆转，限制小胶质细胞形态分布的变化。
TP1989	NEP(1-40) Nogo-66 (1-40)
	Peptide fragment corresponding to residues 1 - 40 of Nogo-66, the domain of the myelin protein Nogo that inhibits axonal outgrowth. Acts as a competitive antagonist at the Nogo-66 receptor (NgR); blocks Nogo-66- and CNS myelin-induced inhibition of axonal
TP1989L	Nogo-66 (1-40) aceate ( 475221-20-6 Free base)
	Nogo-66 (1-40) aceate (475221-20-6 Free base) 是对应于 Nogo-66 残基 1 - 40 的肽片段，Nogo-66 是抑制轴突生长的髓磷脂蛋白 Nogo 的结构域。Nogo-66 (1-40) aceate 作为 Nogo-66 受体 (NgR) 的竞争性拮抗剂，阻断 Nogo-66 和 CNS 髓磷脂诱导的轴突生长抑制，但不会减少髓磷脂相关糖蛋白 (MAG) 体外抑制神经突生长。Nogo-66 (1-40) aceate 促进体内脊髓损伤后半切脊髓轴突的再生和运动恢复。

化合物

Cat.No: TP2185

Target: Others

NGR peptide Trifluoroacetate

Cat.No: TP1771

Aminopeptidase N Ligand (CD13) NGR peptide

Cat.No: T76568

cangrelor tetrasodium

Cat.No: T5036

Target: GPR, P2Y Receptor

Cangrelor free acid

Cat.No: T70335

Cat.No: T81685

Cat.No: TP1989

Synonym: Nogo-66 (1-40)

Nogo-66 (1-40) aceate ( 475221-20-6 Free base)

Cat.No: TP1989L

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00295	NgR Protein, Mouse, Recombinant (hFc) Nogo-66 Receptor,Nogo Receptor,NgR,RTN4R,NOGOR,Reti...	Mouse	HEK293 Cells
	Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be prop...
TMPY-01056	Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc) NOGOR,reticulon 4 receptor,NGR	Human	HEK293 Cells
	Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 73 kDa and the accession number is Q9BZR6.
TMPY-03144	Nogo Receptor/RTN4R Protein, Human, Recombinant (His) NGR,reticulon 4 receptor,NOGOR	Human	HEK293 Cells
	Nogo Receptor/RTN4R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9BZR6.
TMPY-01163	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His) Rtn4r,NgR,NgR1,reticulon 4 receptor,NOGOR	Mouse	HEK293 Cells
	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is Q99PI8.
TMPY-01221	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc) NgR1,reticulon 4 receptor,NgR,Rtn4r,NOGOR	Mouse	HEK293 Cells
	Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 73.8 kDa and the accession number is Q99PI8.
TMPK-01200	Nogo Receptor/RTN4R Protein, Cynomolgus, Recombinant (His) NGR,NOGOR,RTN4R,NgR1,Nogo receptor,Nogo-66...	Cynomolgus	HEK293 Cells
	NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes.
TMPJ-00277	NgR3 Protein, Human, Recombinant (His) NGRL2,Nogo Receptor-Like 2,Reticulon-4 Receptor-Lik...	Human	HEK293 Cells
	Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration ...
TMPY-01151	IFNGR1 Protein, Human, Recombinant (His) IMD27B,IFNGR,interferon gamma receptor 1,CD119,IMD2...	Human	HEK293 Cells
	IFNGR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.3 kDa and the accession number is A0A0S2Z3Y2.
TMPY-02355	IFNGR1 Protein, Mouse, Recombinant (His) interferon gamma receptor 1,Nktar,interferon γ receptor 1,IF...	Mouse	HEK293 Cells
	IFNGR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P15261.
TMPH-02452	Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His)	MeV	E. coli
	Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His) is expressed in E. coli expression system with N-10xHis and C-Avi tag. The predicted molecular weight is 61.8 kDa and the accession number is P69356.
TMPH-03379	Synaptogyrin-1/SYNGR1 Protein, Rat, Recombinant (His)	Rat	E. coli
	May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation. Involved in the regulation of short-term and long-term synaptic plasticity. Synaptogyrin-1/SYNGR1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 31.7 kDa and the accession number is Q62876.
TMPY-03668	IFNGR1 Protein, Cynomolgus, Recombinant (His) interferon γ receptor 1,interferon gamma receptor 1	Cynomolgus	HEK293 Cells
	IFNGR1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is G7P327.
TMPY-02122	IFNGR2 Protein, Mouse, Recombinant (His) interferon γ receptor 2 (interferon γ transducer 1),interfer...	Mouse	HEK293 Cells
	Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2. IFNGR2 is a component of the IFNgamma receptor complex al...
TMPY-02354	IFNGR1 Protein, Mouse, Recombinant (hFc) IFN-gammaR,Ifgr,interferon γ receptor 1,IFN-γR,CD119,Nktar,I...	Mouse	HEK293 Cells
	IFNGR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53 kDa and the accession number is P15261.
TMPY-03346	IFNGR1 Protein, Rat, Recombinant (hFc) interferon gamma receptor 1,interferon γ receptor 1	Rat	HEK293 Cells
	IFNGR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q6P6T3.
TMPY-03379	IFNGR1 Protein, Cynomolgus, Recombinant (hFc) interferon gamma receptor 1,interferon γ receptor 1	Cynomolgus	HEK293 Cells
	IFNGR1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.8 kDa and the accession number is G7P327.
TMPY-05831	IFNGR1 Protein, Human, Recombinant (hFc) IFNGR,interferon gamma receptor 1,IMD27B,CD119,inte...	Human	HEK293 Cells
	IFNGR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.51 kDa and the accession number is A0A0S2Z3Y2.

重组蛋白

NgR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00295

Species: Mouse

Expression System: HEK293 Cells

Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-01056

Species: Human

Expression System: HEK293 Cells

Nogo Receptor/RTN4R Protein, Human, Recombinant (His)

Cat.No: TMPY-03144

Species: Human

Expression System: HEK293 Cells

Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01163

Species: Mouse

Expression System: HEK293 Cells

Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01221

Species: Mouse

Expression System: HEK293 Cells

Nogo Receptor/RTN4R Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01200

Species: Cynomolgus

Expression System: HEK293 Cells

NgR3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00277

Species: Human

Expression System: HEK293 Cells

IFNGR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01151

Species: Human

Expression System: HEK293 Cells

IFNGR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02355

Species: Mouse

Expression System: HEK293 Cells

Measles virus (MeV) (strain Leningrad-16) Fusion glycoprotein F0 (Avi & His)

Cat.No: TMPH-02452

Species: MeV

Expression System: E. coli

Synaptogyrin-1/SYNGR1 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03379

Species: Rat

Expression System: E. coli

IFNGR1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03668

Species: Cynomolgus

Expression System: HEK293 Cells

IFNGR2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02122

Species: Mouse

Expression System: HEK293 Cells

IFNGR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02354

Species: Mouse

Expression System: HEK293 Cells

IFNGR1 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03346

Species: Rat

Expression System: HEK293 Cells

IFNGR1 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-03379

Species: Cynomolgus

Expression System: HEK293 Cells

IFNGR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05831

Species: Human

Expression System: HEK293 Cells

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