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Cat. No. | Product Name | Target | Signaling Pathways |
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T9000 |
Pyrimorph
|
Antifungal | Microbiology/Virology |
Pyrimorph 是一种杀真菌剂,对 oomycetes 具有良好抑菌活性。 | |||
T5881 |
Fluazinam
|
Antifungal | Microbiology/Virology |
Fluazinam 是一种具有广谱抗真菌活性的吡啶胺类杀菌剂,对核盘菌群的菌丝生长有很强的抑制作用。 | |||
T5580 |
1-Naphthaleneacetic acid potassium salt
α-萘醋酸钾,α-Naphthaleneacetic acid,Potassium alpha-naphthylacetate,Potassium 1-Naphthaleneacetate,1-NAA Potassium Salt |
Phospholipase | Metabolism |
1-Naphthaleneacetic acid potassium salt (1-NAA Potassium Salt) 是一种合成的植物生长素,能够促进植物生长,也是一种PLA2抑制剂,IC50=13.16 μM。 | |||
T36141 |
Boscalid
|
Mitochondrial Metabolism | Metabolism |
Boscalid 是一种广谱羧酰胺类杀菌剂,通过与线粒体复合物 II/琥珀酸脱氢酶的泛醌位点结合来抑制真菌呼吸。 | |||
T68282 |
Pyraziflumid
|
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Pyraziflumid is a fungicide. Pyraziflumid is a novel member of succinate dehydrogenase inhibitor fungicides (SDHI). The average EC50 value was 0.0561 (±0.0263)μg/ml for mycelial growth. There was no cross-resistance between pyraziflumid and the widely used fungicides carbendazim, dimethachlon and the phenylpyrrole fungicide fludioxonil. | |||
T41034 |
Triclopyricarb
氯啶菌酯,SYP-7017 |
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Triclopyricarb (SYP-7017) is a strobilurin fungicide that can be used in crops disease control. Triclopyricarb inhibits mycelial growth with EC 50 values ranged from 0.006 μg/mL to 0.047 μg/mL. | |||
T62167 |
BI-10
|
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BI-10 是一种抗真菌化合物。BI-10 与氟康唑联合用药能够抑制菌丝的生长,积累 ROS,减少线粒体膜电位 (MMP),改变膜通透性。 | |||
T36822 |
Benzovindiflupyr
|
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Benzovindiflupyr is a fungicide.1It inhibits mitochondrial complex II, also known as succinate dehydrogenase (SDH; IC50= 5.2 nM), and mycelial growth ofS. sclerotiorum(EC50= 0.011 μg/ml). Benzovindiflupyr (60 μg/ml) completely protects eggplant leaves fromS. sclerotioruminfection. Formulations containing benzovindiflupyr have been used to control various fungal diseases in agriculture. 1.Gao, Y., He, L., Zhu, J., et al.The relationship between features enabling SDHI fungicide binding to the Sc-S... | |||
T35742 |
IKD-8344
|
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IKD-8344 is a macrocyclic dilactone originally isolated from an actinomycete species and has diverse biological activities, including anticancer, antimicrobial, and anthelmintic properties.1,2,3 It is cytotoxic to L5178Y murine leukemia cells (IC50 = 0.54 ng/ml).1 IKD-8344 inhibits growth of the mycelial form of C. albicans (MIC = 6.25 μg/ml) and potentiates the activity of polymyxin B against the multidrug-resistant pathogenic bacterium B. cenocepacia.2,3 It is active against T. spiralis in vit... | |||
T35423 |
7-oxo Staurosporine
|
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7-oxo Staurosporine is an antibiotic originally isolated from S. platensis with diverse biological activites. It inhibits PKC, PKA, phosphorylase kinase, EGFR, and c-Src in vitro (IC50s = 9, 26, 5, 200, and 800 nM, respectively). 7-oxo Staurosporine induces cell cycle arrest in the G2/M phase in human leukemia K562 cells with a minimal effective dose (MED) of 30 ng/ml. It is cytotoxic to P388 mouse leukemia cells that are resistant and susceptible to doxorubicin . 7-oxo Staurosporine inhibits gr... | |||
T41322 |
Dimethomorph
|
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Dimethomorph 是一种吗啉类杀菌剂,属于甾醇生物合成抑制剂类杀菌剂,可抑制真菌细胞壁的形成。Dimethomorph 抑制了oomycete fungi,P. citrophthora,P. parasitica,P. capsici,和P. infestans 的菌丝生长 (EC50=0.14 μg/mL,0.38 μg/mL,<0.1 μg/mL 和 0.16-0.3 μg/mL),但是对绿藻物种C. vulgaris 和S. obliquus 的活性较低 (EC50=47.46 μg/mL 和 44.87 μg/mL)。在 MDA-kb2 人乳腺癌细胞的报告基因分析中,Dimethomorph 抑制雄激素受体 (AR) 的活性,而在酵母抗雄激素筛选中不起作用 (IC20=0.263 μM 和 38.5 μM)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3S1960 |
Kakuol
|
Antifungal | Microbiology/Virology |
Kakuol 是一种有抗真菌活性的天然产物。 | |||
T19962 |
Xyloidone
NSC-106453,NSC106453,Dehydro-α-lapachone,NSC 106453,Dehydrolapachone,脱氢拉帕醌,NSC 629748 |
Antifungal | Microbiology/Virology |
Xyloidone (NSC-106453) 具有抗真菌活性,在 0.4-33.3 mg/L 的范围内完全抑制 B. cinerea、Colletotrichum acutatum Simmonds、Colletotrichum gloeosporioides Simmonds、M. grisea 和 Pythium ultimum Trow 的菌丝生长。 |