Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15038 |
Momelotinib sulfate
CYT387 sulfate salt |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3. | |||
T70823 |
Momelotinib HCl
|
||
Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients. | |||
T1849 |
Momelotinib
CYT11387,CYT387,LM-1149 |
Apoptosis; JAK; Autophagy | Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Momelotinib (LM-1149) 是一种 ATP 竞争性的 JAK1/JAK2抑制剂,IC50值分别为 11 nM/18 nM。 | |||
T15037 |
Momelotinib Mesylate
CYT387 (Mesylate) |
JAK | Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells |
Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3. |