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Cat. No.	Product Name	Target	Signaling Pathways
T3256	MMAF 一甲基澳瑞他汀 F,MonoMethyl auristatin F	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	MMAF (MonoMethyl auristatin F) 是一种抗有丝分裂剂，通过阻断微管蛋白的聚合来抑制细胞分裂，用作抗肿瘤药物和抗体偶联药物的细胞毒性成分。
T12081	MMAF-OMe Monomethyl auristatin F methyl ester
	MMAF-OMe (Monomethyl auristatin F methyl ester) 是一种抗微管蛋白剂，能够抑制 MDAMB435/5T4，MDAMB361DYT2，MDAMB468 和 Raji (5T4-) 这四种肿瘤细胞，IC50值分别为 0.056 nM，0.166 nM，0.183 nM 和 0.449 nM。它也是ADC 细胞毒素。
T39897	DBCO-PEG4-MMAF DBCO-PEG4-MMAF
	DBCO-PEG4-MMAF is an antibody-drug conjugate (ADC) component that exhibits potent antitumor activity. It combines the tubulin polymerization inhibitor MMAF with a cleavable linker, DBCO-PEG4, to target cancer cells effectively.
T38830	Modified MMAF-C5-COOH Modified MMAF-C5-COOH
	Modified MMAF-C5-COOH is a drug-linker conjugate for ADC.
T39748	DBCO-PEG4-Val-Cit-PAB-MMAF DBCO-PEG4-Val-Cit-PAB-MMAF
	DBCO-PEG4-Val-Cit-PAB-MMAF is a chemical compound that comprises a cleavable 4 unit polyethylene glycol antibody-drug conjugate (ADC) linker known as DBCO-PEG4-Val-Cit-PAB, and a highly effective inhibitor of tubulin polymerization called MMAF. This compound serves as a valuable component in the synthesis of ADCs.
T39238	DBM-MMAF
	DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC).
T10949	D8-MMAF Monomethylauristatin F D8	Others	Others
	D8-MMAF is a microtubule destroyer, deuterated form of MMAF.
T16121	MMAF Hydrochloride Monomethylauristatin F Hydrochloride	Others	Others
	MMAF Hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF Hydrochloride is an effective tubulin polymerization inhibitor and is used as an antitumor compound.
T18534	PEG4-aminooxy-MMAF	Others	Others
	PEG4-aminooxy-MMAF is a drug-linker conjugate designed for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. It incorporates MMAF, a powerful antitubulin agent, connected through a non-cleavable PEG4 linker[1].
T16122	MMAF sodium Monomethylauristatin F sodium	ABC	Membrane transporter/Ion channel
	MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerization inhibitor and is used as an antitumor agent.
T19269	D8-MMAF hydrochloride	Others	Others
	D8-MMAF hydrochloride is a deuterated form of MMAF hydrochloride, which is a microtubule destroyer.
T27975	MAL-PEG4-MMAF
	MAL-PEG4-MMAF is a maleimido functionalized derivative of MMAF (Monomethyl auristatin F) with PEG4 linker. The maleimido functional group can be easily conjugated to protein carriers (such as antibody or enzyme). MAL-PEG4-MMAF is a useful precursor for ma
T18306	MC-Alkyl-Hydrazine Modified MMAF	Others	Others
	MC-Alkyl-Hydrazine Modified MMAF is a potent antitumor drug-linker conjugate for ADC, incorporating Modified MMAF, a tubulin inhibitor, through a noncleavable MC-Alkyl-Hydrazine linkage[1].
T18326	MC-Val-Cit-PAB-MMAF	Others	Others
	MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavable linker, MC-Val-Cit-PAB.
T18251	MAL-di-EG-Val-Cit-PAB-MMAF	Others	Others
	MAL-di-EG-Val-Cit-PAB-MMAF refers to a chemical compound that comprises the linker (MAL-di-EG-Val-Cit-PAB) and the potent blocker of tubulin polymerization (MMAF, Monomethyl auristatin F)[1].
T74177	Modified MMAF
	Modified MMAF 是一种用于构建 Antibody-drug Conjugate (ADC) 的 ADC 细胞毒素，适用于癌症靶向研究。
T82382	Fmoc-MMAF-OMe
	Fmoc-MMAF-OMe，一种具有Fmoc保护基团的抗癌剂和微管蛋白聚合抑制剂，其活性成分MMAF作为经典抗体偶联药物（ADCs）中的细胞毒性（ADC Cytotoxin）组分。
T83129	Amidate-VC-PAB-MMAF
	Amidate-VC-PAB-MMAF 是结合了可降解的ADC linker (Amidate-VC-PAB) 与有效微管蛋白聚合抑制剂MMAF的化合物。其应用于抗体偶联活性分子（ADC）的合成，并能减少ADC的脱靶效应。
T80883	Val-Cit-PAB-MMAF
	Val-Cit-PAB-MMAF为抗体偶联药物(ADC)活性组分，其结构由ADC linker（肽Val-Cit-PAB）与高效的微管蛋白聚合抑制剂MMAF通过偶联形成。
T81715	N3-PEG3-VC-PAB-MMAF
	N3-PEG3-VC-PAB-MMAF（Comp T-88-5）为药物连接物偶联物，结合了ADC连接物N3-PEG3-VC-PAB与微管蛋白抑制剂MMAF，作为点击化学试剂，在具有Azide基团的特点下，能够通过铜催化叠氮-炔环加成反应（CuAAc)与含Alkyne基团的分子反应，同时也能通过菌株促进炔-叠氮环加成反应（SPAAC）与含DBCO或BCN基团的分子作用。
T77894	Val-Cit-PAB-MMAF sodium
	Val-Cit-PAB-MMAFsodium为抗体药物偶联物（ADC）的活性组分，其结构由ADC连接子（肽类连接子Val-Cit-PAB）与高效微管蛋白聚合抑制剂MMAF通过偶联形成。
T77892	Mal-PEG8-Val-Cit-PAB-MMAF
	Mal-PEG8-Val-Cit-PAB-MMAF 是一种用于抗体药物偶联体 (ADC) 的药物-连接物复合体 (drug-linker conjugate for ADC)。该化合物由一个可降解的 ADC linker 以及有效的微管蛋白抑制剂 MMAE 组成。
T16031	McMMAF Maleimidocaproyl monomethylauristatin F	Microtubule Associated	Cytoskeletal Signaling
	McMMAF 是一种保护基团共轭的 MMAF。它是一种具有马来酰亚胺基己酰基接头（MC 接头）的 MMAF 衍生物， MMAF 是一种有效的微管蛋白聚合抑制剂。它可与抗体或其他蛋白质或生物聚合物结合。
T74880	Cys-McMMAF
	Cys-McMMAF 是 AlMcMMAF 释放的有效载荷，AlMcMMAF 是一种抗 5T4 的人源化 A1 抗体，通过马来酰咪唑丙基连接物偶联到微管破坏 MMAF 。Cys-McMMAF 对两种肿瘤小鼠模型(H1975 和 MDA-MB-361-DYT2 模型) 均有抑癌效果。

化合物

Cat.No: T3256

Synonym: 一甲基澳瑞他汀 F,MonoMethyl auristatin F

Target: Others, Microtubule Associated

Cat.No: T12081

Synonym: Monomethyl auristatin F methyl ester

DBCO-PEG4-MMAF

Cat.No: T39897

Synonym: DBCO-PEG4-MMAF

Modified MMAF-C5-COOH

Cat.No: T38830

Synonym: Modified MMAF-C5-COOH

DBCO-PEG4-Val-Cit-PAB-MMAF

Cat.No: T39748

Synonym: DBCO-PEG4-Val-Cit-PAB-MMAF

Cat.No: T39238

Cat.No: T10949

Synonym: Monomethylauristatin F D8

Target: Others

MMAF Hydrochloride

Cat.No: T16121

Synonym: Monomethylauristatin F Hydrochloride

Target: Others

PEG4-aminooxy-MMAF

Cat.No: T18534

Target: Others

Cat.No: T16122

Synonym: Monomethylauristatin F sodium

Target: ABC

D8-MMAF hydrochloride

Cat.No: T19269

Target: Others

MAL-PEG4-MMAF

Cat.No: T27975

MC-Alkyl-Hydrazine Modified MMAF

Cat.No: T18306

Target: Others

MC-Val-Cit-PAB-MMAF

Cat.No: T18326

Target: Others

MAL-di-EG-Val-Cit-PAB-MMAF

Cat.No: T18251

Target: Others

Modified MMAF

Cat.No: T74177

Fmoc-MMAF-OMe

Cat.No: T82382

Amidate-VC-PAB-MMAF

Cat.No: T83129

Val-Cit-PAB-MMAF

Cat.No: T80883

N3-PEG3-VC-PAB-MMAF

Cat.No: T81715

Val-Cit-PAB-MMAF sodium

Cat.No: T77894

Mal-PEG8-Val-Cit-PAB-MMAF

Cat.No: T77892

Cat.No: T16031

Synonym: Maleimidocaproyl monomethylauristatin F

Target: Microtubule Associated

Cat.No: T74880

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