Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7841 |
MK 571
MK-571钠盐,L660711,L-660711,MK-571 |
LTR | Immunology/Inflammation |
MK 571 (L660711) 是一种具有口服活性的 CysLT1 受体拮抗剂。 | |||
T3148 |
MK-571 sodium
L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid |
Leukotriene Receptor; LTR | GPCR/G Protein; Immunology/Inflammation |
MK-571 sodium (L-660711 sodium salt) 是一种可口服的选择性白三烯 D4受体拮抗剂,在豚鼠和人肺膜的 Ki 分别为0.22 和 2.1 nM。 | |||
T19674 |
Verlukast
MK 0679,MK-679,L 668,019,MK 679,L 668019,L-668,019 |
||
Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homogenates and dimethyl sulfoxide diffe |