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Search Results for " mim "

Targets Recommended: BCL

26

抑制剂 & 化合物

4

天然产物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T12041	MIM1 Inhibitor of Mcl-1	BCL	Apoptosis
	MIM1 (Inhibitor of Mcl-1) 是一种骨髓细胞因子 1 抑制剂。
T17000	Tavilermide MIM-D3	Trk receptor	Tyrosine Kinase/Adaptors
	Tavilermide is a selective and partial agonist of TrkA or a nerve growth factor mimetic.
T40199	Tulmimetostat CPI-0209	Histone Methyltransferase	Chromatin/Epigenetic
	Tulmimetostat (CPI-0209) 是一种具有口服活性的 EZH1/EZH2 抑制剂。Tulmimetostat 有抗肿瘤活性，用于研究卵巢癌和晚期实体瘤。
T13215	N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide N-(3-氯-4-吗啉代苯基)-N'-羟基甲脒,TS-011	Others	Others
	N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide (TS-011) 是一种选择性 20-羟基二十碳四烯酸合成抑制剂。
TP1541L	BDC2.5 mimotope 1040-31 acetate BDC2.5 mimotope 1040-31 acetate(329696-49-3 free base)	Others	Others
	BDC2.5 mimotope 1040-31 acetate(329696-49-3 free base) 一种用于致糖尿病 T 细胞克隆 BDC2.5 的有效激动肽 (mimotope)。它可以刺激 BDC2.5 细胞，使细胞对这种模拟表位表现出良好的反应。 1040-31 肽对 BDC2.5 TCR Tg+（转基因）T 细胞具有特异性。该肽也称为 p31。
T76931	Birtamimab
	Birtamimab (NEOD001) 为一研究性单克隆抗体，特异性且选择性地靶向并清除淀粉样蛋白，主要应用于轻链淀粉样变性的研究。
TP1679	BDC2.5 mimotope 1040-51
	BDC2.5 mimotope 1040-51 is a mimotope peptide for diabetogenic T cell clone BDC2.5. isolated from non-obese diabetic mice.This is a effectively agonistic peptide (mimotope) for diabetogenic T cell clone BDC2.5. from non-obese diabetic (NOD) mice. T cells
T82908	BDC2.5 mimotope 1040-31 TFA
	BDC2.5 mimotope 1040-31 TFA，一种针对糖尿病T细胞克隆BDC2.5的强活性激动肽，具备对BDC2.5 TCR Tg+T细胞的高度特异性。
T26189	Setomimycin AM 2947,Antibiotic A 39183B,AM2947,AM-2947
	Setomimycin is an antibiotic against Gram positive bacteria, including mycobacteria.
T82683	Connexin mimetic peptide 40GAP27
	Connexin mimetic peptide 40GAP27 是一种生物活性肽，对应于主要的血管连接蛋白Cx40第二个细胞外环的GAP27结构域（40Gap27）。该化合物在研究氧化应激所致的损伤以及间隙连接通讯机制中有应用。40Gap27能够在给药后减少内皮依赖性的内膜下平滑肌的超极化现象。
T83106	Anselamimab
	Anselamimab (CAEL-101) 为一种靶向血清淀粉样蛋白 A1 (SAA1) 的人源 IgG1-κ 抗淀粉样蛋白原纤维抗体。
T64417	N'-(2,4-Dimethylphenyl)-N-methylformimidamide hydrochloride
	N'-(2,4-Dimethylphenyl)-N-methylformimidamide hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64417，CAS号为 51550-40-4。
T31851	Formiminoglutamic acid NSC-334078,NSC334078,NSC 334078
	Formiminoglutamic acid is used to indicate folic acid deficiency and megaloblastic anemia of pregnancy with the measurement in the urine after oral administration of histidine.
T75656	Calcimycin hemimagnesium
	Calcimycin (A-23187) hemimagnesium，一种具有抗生素功能的独特二价阳离子离子载体（例如钙离子和镁离子），通过提高细胞内钙浓度而诱导Ca2+依赖性细胞死亡。该化合物还能抑制革兰氏阳性细菌和部分真菌生长，同时抑制ATP酶活性并解耦哺乳动物细胞的氧化磷酸化（OXPHOS），触发细胞凋亡（apoptosis）。
TP1541	BDC2.5 mimotope 1040-31
	This is a effectively agonistic peptide (mimotope) for diabetogenic T cell clone BDC2.5. It can stimulate BDC2.5 cells with cells showing good response to this mimotope. 1040-31 peptide is specific for BDC2.5 TCR Tg+ (transgenic) T cells. This peptide is
TP1601	BDC2.5 mimotope 1040-31 TFA(329696-49-3 free base) BDC2.5 mimotope 1040-31 TFA
	This is a strongly agonistic peptide (mimotope) for diabetogenic T cell clone BDC2.5.
T33387L	Mimbane hydrochloride W2291A,W-2291A,W 2291A
	Mimbane hydrochloride is a biochemical.
T33387	Mimbane NSC-76808,NSC76808,NSC 76808
	Mimbane is a biochemical.
T82907	BDC2.5 Mimotope 1040-63
	BDC2.5 Mimotope 1040-63是具有生物活性的肽，广泛应用于1型糖尿病（T1D）研究中的TCR转基因模型（BDC2.5）模拟表位。T1D是一种涉及自身免疫系统对胰岛β细胞的T细胞介导损害的自身免疫性疾病。BDC2.5模拟表位在研究胰岛素产生细胞遭到自身反应性T细胞破坏的过程中，对支持抗原肽实现向胰岛自身抗原特异性T细胞的抗原呈递具有重要作用。
T63389	AHR antagonist 5 hemimaleate
	AHR antagonist 5 hemimaleate 是一种口服具有活力的芳香烃受体 (AHR) 的有效拮抗剂 (IC50< 0.5 μM)。AHR antagonist 5 hemimaleate 联合检测点抑制剂 anti-PD-1 对肿瘤生长表现出抑制作用。
T69344	Mimosinamine
	Mimosinamine is an inhibitor of amino acid (Phe, Tyr, Trp) hydroxylases.
T66310	Methyl 2-ethoxy-1-((2'-(N-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate
	Methyl 2-ethoxy-1-((2'-(N-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66310，CAS号为 147403-65-4。
T33388	Mimosine methyl ester L-Mimosine methyl ester
	Mimosine methyl ester is a toxic non-protein amino acid chemically similar to tyrosine, that was first isolated from Mimosa pudica.
T28041	Mimopezil ZT-1 LA,Debio-9902-SR,Debio-9902,ZT-1
	Mimopezil is an acetylcholinesterase (AChE) inhibitor.
T82456	EPO mimetic peptide-1 EMP-1
	EPO mimetic peptide-1 (EMP-1)为含20个氨基酸的多肽，该化合物具有促进细胞增殖、影响细胞周期以及诱导网织细胞产生的作用。
T82684	Connexin mimetic peptide 40,37GAP26
	Connexin mimetic peptide 40,37GAP26是一种生物活性肽，对应Cx37和Cx40主要血管连接蛋白的胞外环GAP26结构域，命名基于Cx同源性为37,40Gap26。本化合物主要用于研究间隙连接对环吡嗪酸(CPA)通过啮齿动物髂动脉壁导致的内皮超极化扩散的影响。Cx37和Cx40形成的间隙连接斑块在内皮细胞中高度丰富，而Connexin mimetic peptide 40,37GAP26能抑制内膜下超极化。

化合物

Cat.No: T12041

Synonym: Inhibitor of Mcl-1

Target: BCL

Cat.No: T17000

Synonym: MIM-D3

Target: Trk receptor

Cat.No: T40199

Synonym: CPI-0209

Target: Histone Methyltransferase

N-(3-Chloro-4-morpholinophenyl)-N'-hydroxyformimidamide

Cat.No: T13215

Synonym: N-(3-氯-4-吗啉代苯基)-N'-羟基甲脒,TS-011

Target: Others

BDC2.5 mimotope 1040-31 acetate

Cat.No: TP1541L

Synonym: BDC2.5 mimotope 1040-31 acetate(329696-49-3 free base)

Target: Others

Cat.No: T76931

BDC2.5 mimotope 1040-51

Cat.No: TP1679

BDC2.5 mimotope 1040-31 TFA

Cat.No: T82908

Cat.No: T26189

Synonym: AM 2947,Antibiotic A 39183B,AM2947,AM-2947

Connexin mimetic peptide 40GAP27

Cat.No: T82683

Cat.No: T83106

N'-(2,4-Dimethylphenyl)-N-methylformimidamide hydrochloride

Cat.No: T64417

Formiminoglutamic acid

Cat.No: T31851

Synonym: NSC-334078,NSC334078,NSC 334078

Calcimycin hemimagnesium

Cat.No: T75656

BDC2.5 mimotope 1040-31

Cat.No: TP1541

BDC2.5 mimotope 1040-31 TFA(329696-49-3 free base)

Cat.No: TP1601

Synonym: BDC2.5 mimotope 1040-31 TFA

Mimbane hydrochloride

Cat.No: T33387L

Synonym: W2291A,W-2291A,W 2291A

Cat.No: T33387

Synonym: NSC-76808,NSC76808,NSC 76808

BDC2.5 Mimotope 1040-63

Cat.No: T82907

AHR antagonist 5 hemimaleate

Cat.No: T63389

Cat.No: T69344

Methyl 2-ethoxy-1-((2'-(N-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

Cat.No: T66310

Mimosine methyl ester

Cat.No: T33388

Synonym: L-Mimosine methyl ester

Cat.No: T28041

Synonym: ZT-1 LA,Debio-9902-SR,Debio-9902,ZT-1

EPO mimetic peptide-1

Cat.No: T82456

Synonym: EMP-1

Connexin mimetic peptide 40,37GAP26

Cat.No: T82684

Cat. No.	Product Name	Target	Signaling Pathways
T6569	Mimosine Leucenine,NSC 69188,含羞草素,Leucenol,L-Mimosine	Others	Others
	Mimosine (Leucenol) 是一种酪氨酸类似物，具有抗癌和抗炎等活性。它可通过其强大的铁结合活性作为抗氧化剂，是一种 Fe(III) 螯合剂。它作用于人类白血病细胞，通过金属离子螯合、线粒体激活和诱导活性氧产生来诱导细胞凋亡。
T19281L	Dihydroxyacetone phosphate hemimagnesium salt hydrate Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base)	Others	Others
	Dihydroxyacetone phosphate hemimagnesium salt hydrate 也称为磷酸二羟基丙酮或 3-羟基-2-氧代丙基磷酸。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 存在于从细菌到人类的所有生物中。在人类体内， Dihydroxyacetone phosphate hemimagnesium salt hydrate参与许多酶促反应。 Dihydroxyacetone phosphate hemimagnesium salt hydrate 已被研究用于治疗淋巴瘤、大细胞淋巴瘤、弥漫性淋巴瘤。
T73763	Dihydroxyacetone phosphate hemimagnesium hydrate
	Dihydroxyacetone phosphate 是脂质生物合成和糖酵解中的重要中间产物，参与卡尔文循环和糖酵解等多种代谢途径。此化合物与醛缩酶缺乏症，一种先天性代谢缺陷，相关。
T6569L	Mimocine Mimocine
	Mimosine, a plant amino acid, is known to act as a normoxic inducer of hypoxia-inducible factor (HIF).

天然产物

Cat.No: T6569

Synonym: Leucenine,NSC 69188,含羞草素,Leucenol,L-Mimosine

Target: Others

Dihydroxyacetone phosphate hemimagnesium salt hydrate

Cat.No: T19281L

Synonym: Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base)

Target: Others

Dihydroxyacetone phosphate hemimagnesium hydrate

Cat.No: T73763

Cat.No: T6569L

Synonym: Mimocine

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02384	MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP) metastasis suppressor 1,MIMB,MIM,MIM	Human	E. coli
	MTSS1 (Metastasis suppressor 1), also known as Missing in metastasis (MIM), is a tissue-specific regulator of plasma membrane dynamics. MTSS1 is well described for its function as a metastasis suppressor gene and is expressed in a variety of tissues. MTSS1 might be involved in shaping neuronal membranes in vivo. MTSS1 deforms phosphoinositide-rich membranes through its I-BAR domain and interacts with actin monomers through its WH2 domain. MTSS1/MIM was first identified as a metastasis suppressor...
TMPH-02114	SMIM4 Protein, Human, Recombinant (His)	Human	E. coli
	N/A. SMIM4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 11.5 kDa and the accession number is Q8WVI0.
TMPU-00002	SOS1-Cat Protein, Human, Recombinant (His) SOS-1,Son of sevenless homolog 1	Human	E. coli
	Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1) [MIM:135300]; also known as GINGF1. Gingival fibromatosis is a rare overgrowth condition. Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4) [MIM:610733]. NS4 is an autosomal dominant disorder characterized by dysmorphic facial features, short stature, hypertelorism, cardiac anomalies, deafness, motor delay, and a bleeding diathesis. It is a genetically heterogeneous and relatively common syndrome, with an estimated incid...
TMPJ-00599	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His) TIM3,Hepatitis A virus cellular receptor 2,KIM-3,T-cell memb...	Human	HEK293 Cells
	Hepatitis A virus cellular receptor 2（HAVCR2）is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the immunoglobulin superfamily, and TIM family of proteins. The protein regulates macrophage activation. It inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and it is receptor for LGALS9. CD4 (MIM 186940)-positive T ...

重组蛋白

MTSS1 Protein, Human, Recombinant (aa1-250, His & MBP)

Cat.No: TMPY-02384

Species: Human

Expression System: E. coli

SMIM4 Protein, Human, Recombinant (His)

Cat.No: TMPH-02114

Species: Human

Expression System: E. coli

SOS1-Cat Protein, Human, Recombinant (His)

Cat.No: TMPU-00002

Species: Human

Expression System: E. coli

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00599

Species: Human

Expression System: HEK293 Cells

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