Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T33380 |
MI-389
|
PROTACs | PROTAC |
MI-389 is a protein degrader, targeting the translation termination factor G1 to S phase transition 1 (GSPT1). | |||
T39512 |
Thalidomide-NH-C6-NH-Boc
Thalidomide-NH-C6-NH-Boc |
||
Thalidomide-NH-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate containing the cereblon ligand derived from Thalidomide and a linker utilized in the synthesis of MI-389 (compound 22). MI-389 is a highly effective phthalimide PROTAC degrader developed from the multi-targeted receptor tyrosine kinase inhibitor sunitinib. |