Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6967 |
RHPS4
RHPS 4 methosulfate,NSC714187 |
Apoptosis; Telomerase | Apoptosis; DNA Damage/DNA Repair |
RHPS4 (RHPS 4 methosulfate) 是 DNA 损伤诱导剂,是一种有效的亚微摩尔端粒酶抑制剂,IC50为0.33 μM。 | |||
T9598 | NCATS-SM1441 | ||
T25141 |
BDM14471
BDM-14471,BDM 14471 |
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BDM14471 is a selective inhibitor of hydroxamate PfAM1. | |||
T62916 |
GEM144
|
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GEM144 是一种有效的、口服具有活力的 DNA polymerase α(POLA1) 和HDAC 11 双重抑制剂。GEM144 能够诱导 p53 乙酰化、激活 p21,将细胞周期阻滞在 G1/S 期,并诱导细胞凋亡。 | |||
T70033 |
NCATS-SM1440
|
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NCATS-SM1440 is a Lactate Dehydrogenase Inhibitor with Optimized Cell Activity and Pharmacokinetic Properties. | |||
T8791 | HlyU inhibitor CM14 (1025E12) | ||
HlyU inhibitor CM14 (1025E12) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T8791,CAS号为 588678-13-1。 | |||
T36468 |
ARN14988
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ARN14988 is a potent inhibitor of acid ceramidase (IC50 = 12.8 nM for the human enzyme). It inhibits acid ceramidase activity and increases levels of C16 dihydro ceramide and C16 ceramide in A375, G361, M14, MeWo, MNT-1, and SK-MEL-28 melanoma cells. ARN14988 also reduces growth of A375 and G361 melanoma cells (EC50s = 41.8 and 67.7 μM, respectively). |