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Search Results for " lansoprazole "

13

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0674	Lansoprazole 兰索拉唑,A-65006,AG-1749	Proton pump; Phospholipase; Antibacterial	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Lansoprazole (A-65006) 是一种可抑制胃酸生成的质子泵抑制剂。它是中性鞘磷脂酶的外泌体抑制剂。
T20155	Lansoprazole sulfone	Others	Others
	Lansoprazole sulfone 是胃泵抑制剂Lansoprazole 的代谢产物。
T1021	(R)-Lansoprazole Dexlansoprazole,右旋兰索拉唑,T 168390,TAK 390,R-(+)-Lansoprazole	Proton pump	Membrane transporter/Ion channel
	(R)-Lansoprazole (T 168390) 是Lansoprazole 的R 型异构体。Lansoprazole 是口服有效的质子泵抑制剂，能抑制胃酸生成。Lansoprazole 是中性鞘磷脂酶(N-SMase)的抑制剂(外泌体抑制剂)，能透过血脑屏障。
T20714	Levolansoprazole 左旋兰索拉唑,(S)-Lansoprazole,(-)-Lansoprazole	Proton pump	Membrane transporter/Ion channel
	Levolansoprazole ((S)-Lansoprazole) 是一种质子泵抑制剂，不可逆地抑制壁细胞中 H+/K+ 刺激的 ATPase 泵 (IC50: 5.2 µM)。它还抑制分离的犬壁细胞中的酸形成(IC50：82 µM)。 (R)-和 (S)-兰索拉唑均具有药理活性，具有相似的效力。
T11816	Lansoprazole-d4 AG-1749 D4,Lansoprazole D4	Proton pump	Membrane transporter/Ion channel
	Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.
T21128	Lansoprazole sulfide Lansoprazole impurity C,AG-1777,EC 600-451-9,H 225/18,K-1252
	Lansoprazole sulfide is an impurity of Lansoprazole, which is a gastric pump inhibitor.
T11817	Lansoprazole Sulfide D4	Proton pump	Membrane transporter/Ion channel
	Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole.
T70978	5-Hydroxy Lansoprazole Sulfide
	5-Hydroxy Lansoprazole Sulfide is an inhibitor of fatty acid synthase (FASN). FASN, which is responsible for de-novo synthesis of lipids, has been found to be overexpressed in cancerous tissue. 5-Hydroxy Lansoprazole Sulfide specifically inhibits enoyl reductase, and was found to more effectively inhibit FASN function than lansoprazole and was also more efficient at regulating NHEJ repair of oxidative DNA damage via PARP1.
T29704	AG-1812 free base UNII-6RI44GB0V9,HE078804,AC1MIZB6,Lansoprazole disulfide active metabolite
	ABT-1812 is a bio-active chemical.
T29705	AG-2000 Free Base Lansoprazole sulfenamide active metabolite
	AG-2000 Free Base is a bio-active chemical. Detailed information has not been published.
T70977	JMN13497
	JMN13497 is an precursor compound to for synthesis of scytonemin. Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive on...
T14051	5-Hydroxylansoprazole AG1908	Proton pump	Membrane transporter/Ion channel
	5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor that effectively treats various peptic diseases[1][2]. The metabolism of Lansoprazole occurs through CYP2C19, resulting in the formation of 5-Hydroxylansoprazole.
T23586	5-Hydroxylansoprazole sulfone AG1909,AG 1909,AG-1909
	5-hydroxylansoprazole is an in vitro metabolism-dependent CYP2C19 inhibitor.

化合物

Cat.No: T0674

Synonym: 兰索拉唑,A-65006,AG-1749

Target: Proton pump, Phospholipase, Antibacterial

Lansoprazole sulfone

Cat.No: T20155

Target: Others

(R)-Lansoprazole

Cat.No: T1021

Synonym: Dexlansoprazole,右旋兰索拉唑,T 168390,TAK 390,R-(+)-Lansoprazole

Target: Proton pump

Levolansoprazole

Cat.No: T20714

Synonym: 左旋兰索拉唑,(S)-Lansoprazole,(-)-Lansoprazole

Target: Proton pump

Lansoprazole-d4

Cat.No: T11816

Synonym: AG-1749 D4,Lansoprazole D4

Target: Proton pump

Lansoprazole sulfide

Cat.No: T21128

Synonym: Lansoprazole impurity C,AG-1777,EC 600-451-9,H 225/18,K-1252

Lansoprazole Sulfide D4

Cat.No: T11817

Target: Proton pump

5-Hydroxy Lansoprazole Sulfide

Cat.No: T70978

AG-1812 free base

Cat.No: T29704

Synonym: UNII-6RI44GB0V9,HE078804,AC1MIZB6,Lansoprazole disulfide active metabolite

AG-2000 Free Base

Cat.No: T29705

Synonym: Lansoprazole sulfenamide active metabolite

Cat.No: T70977

5-Hydroxylansoprazole

Cat.No: T14051

Synonym: AG1908

Target: Proton pump

5-Hydroxylansoprazole sulfone

Cat.No: T23586

Synonym: AG1909,AG 1909,AG-1909

Cat. No.	Product Name	Target	Signaling Pathways
T21651	Lansoprazole sodium 兰索拉唑钠,Lansoprazole (sodium), AG-1749 sodium	Proton pump; Phospholipase; Antibacterial	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Lansoprazole sodium (Lansoprazole (sodium)) 是一种质子泵抑制剂，是中性鞘磷脂酶的外泌体抑制剂，能抑制胃酸生成。

天然产物

Lansoprazole sodium

Cat.No: T21651

Synonym: 兰索拉唑钠,Lansoprazole (sodium), AG-1749 sodium

Target: Proton pump, Phospholipase, Antibacterial

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