Cat. No. | Product Name | Target | Signaling Pathways |
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T0680 |
Lamotrigine
LTG,BW430C,拉莫三嗪 |
5-HT Receptor; Sodium Channel; Autophagy | Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
Lamotrigine (BW430C) 是一种抗癫痫剂和情绪稳定剂,可研究癫痫、局灶性癫痫等。。它选择性地阻断电压门控钠离子通道,稳定突触前神经元膜,抑制谷氨酸释放。 | |||
T36482 |
Lamotrigine isethionate
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Water-soluble salt of lamotrigine . Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents. Leach et al (1991) Neurochemical and behavioral aspects of lamotr. Epilepsia 32 S4 PMID:1685439 |Smith and Meldrum (1995) Cardioprotective effect of lamotr. after focal ischemia in rats. Stroke 26 117 PMID:7839380 |Zona and Avoli (1997) Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture. Epilepsia 38 522 PMI... | |||
T60492 |
Lamotrigine hydrate
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Lamotrigine hydrate 是口服有效的抗惊厥剂或抗癫痫剂 ,通过选择性地阻断电压门控Na+通道,稳定突触前神经元膜并抑制谷氨酸释放。Lamotrigine hydrate 可用于研究癫痫、局灶性癫痫等神经性疾病。 |