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Search Results for " ldopa "

14

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5954	Methyldopa hydrate L-甲基多巴,Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate	Dopamine Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Methyldopa hydrate (MK-351 hydrate) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是一种 α-肾上腺素能激动剂，对α2-adrenergic receptors 有选择性。
T6835	Fenoldopam mesylate Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fenoldopam mesylate (Corlopam mesylate) 是一种多巴胺受体D1选择性激动剂。
T38221	N,N-Dipropyldopamine (hydrobromide)
	N,N-Dipropyldopamine is a dopamine receptor agonist.1,2,3 It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum of reserpinized rats (ED50s = 25 and 20 μmol/kg, respectively), as well as reduces homovanillic acid levels in rat striatum when administered at a dose of 80 μmol/kg.1 N,N-Dipropyldopamine (0.5-16 mg/kg) reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.2,3
T15701	Methyldopa hydrochloride L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride	Others	Others
	L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts
T22779	Fenoldopam	Others	Others
	Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).
T20133	Methyldopate hydrochloride Aldomet Ester hydrochloride,Aldomet,Methyldopate HCl,Methyldopa ethyl ester hydrochloride
	Methyldopate HCl is an agent of antihypertensive.
T60241	N-Methyldopamine hydrochloride
	N-Methyldopamine hydrochloride 是肾上腺素在肾上腺髓质中的前体。N-Methyldopamine hydrochloride 是多巴胺 (DA) 的修饰物，并保留了对 DA1 受体 (DA1 receptor) 的激动剂活性。N-Methyldopamine hydrochloride 具有普遍的表面包覆和利用表面儿茶酚进行二次反应的能力。N-Methyldopamine hydrochloride 可用于心力衰竭的研究。
T75537	N-Acetyldopamine dimer-2
	N-Acetyldopamine dimer-2（compound 2）是一种从蝉皮黄色粉末中分离出来的N-acetyldopamine二聚体，具有抗氧化和抗炎作用。它能抑制氧化低密度脂蛋白（LDL）的氧化、ROS的生成、NO的生成以及NF-κB的活性。
T70155	Fenoldopam hydrochloride
	Fenoldopam hydrochloride is a selective D1-like dopamine receptor partial agonist. It acts as a vasodilator in vivo and does not readily cross the blood-brain barrier. Fenoldopam HCl is also an α2-adrenoceptor antagonist in vitro.
T71779	Fenoldopam hydrobromide
	Fenoldopam hydrobromide is a Dopamine D1-receptor agonist that acts as an antihypertensive.
T74081	N-β-alanyldopamine hydrochloride
	N-β-alanyldopamine hydrochloride (NBAD hydrochloride) 是血淋巴中多巴胺的主要衍生物。
T62530	N-Arachidonyldopamine NADA	Cannabinoid Receptor	GPCR/G Protein
	N-Arachidonyldopamine (NADA) 是一种选择性的、强效的内源性 CB1 受体激动剂 (Ki: 250 nM)。N-Arachidonyldopamine 也是一种有效的、选择性 TRPV1 激动剂，其 EC50 值 ~50 nM。
T36206	Methyldopate
	Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension.
T69105	Methyldopa anhydrous
	Methyldopa anhydrous is a Central alpha-2 Adrenergic Agonist. The mechanism of action of methyldopa anhydrous is as an Adrenergic alpha2-Agonist.

化合物

Methyldopa hydrate

Cat.No: T5954

Synonym: L-甲基多巴,Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate

Target: Dopamine Receptor, Adrenergic Receptor

Fenoldopam mesylate

Cat.No: T6835

Synonym: Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐

Target: Dopamine Receptor

N,N-Dipropyldopamine (hydrobromide)

Cat.No: T38221

Methyldopa hydrochloride

Cat.No: T15701

Synonym: L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride

Target: Others

Cat.No: T22779

Target: Others

Methyldopate hydrochloride

Cat.No: T20133

Synonym: Aldomet Ester hydrochloride,Aldomet,Methyldopate HCl,Methyldopa ethyl ester hydrochloride

N-Methyldopamine hydrochloride

Cat.No: T60241

N-Acetyldopamine dimer-2

Cat.No: T75537

Fenoldopam hydrochloride

Cat.No: T70155

Fenoldopam hydrobromide

Cat.No: T71779

N-β-alanyldopamine hydrochloride

Cat.No: T74081

N-Arachidonyldopamine

Cat.No: T62530

Synonym: NADA

Target: Cannabinoid Receptor

Cat.No: T36206

Methyldopa anhydrous

Cat.No: T69105

Cat. No.	Product Name	Target	Signaling Pathways
T0848	L-DOPA 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine	Dopamine Receptor; Endogenous Metabolite	GPCR/G Protein; Metabolism; Neuroscience
	L-DOPA (Levodopa) 是的神经递质多巴胺的代谢前体，具有口服活性。Levodopa 能够透过血脑屏障，并在大脑中转化为多巴胺。Levodopa 具有抗痛觉过敏作用。Levodopa 还具有帕金森氏病的研究潜力。
T0505	Methyldopa L-(-)-α-Methyldopa,MK-351,甲基多巴	Dopamine Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	L-(-)-α-Methyldopa (MK-351) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是 α-肾上腺素能激动剂，对 α2- adrenergic receptors 有选择性。
T40158	N-acetyldopamine NADA,N-乙酰多巴胺
	N-acetyldopamine (NADA) is a catecholamine utilized by insects as a precursor for sclerotization, a process that strengthens their cuticle.
T81710	N-Acetyldopamine dimer-3
	N-Acetyldopamine dimer-3 (compound 11)为Aspongopus chinensis中检出的天然化合物。

天然产物

Cat.No: T0848

Synonym: 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine

Target: Dopamine Receptor, Endogenous Metabolite

Cat.No: T0505

Synonym: L-(-)-α-Methyldopa,MK-351,甲基多巴

Target: Dopamine Receptor, Adrenergic Receptor

N-acetyldopamine

Cat.No: T40158

Synonym: NADA,N-乙酰多巴胺

N-Acetyldopamine dimer-3

Cat.No: T81710

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