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Search Results for " lcarnitine "

14

抑制剂 & 化合物

13

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37516	[(3R)-3-Hydroxydodecanoyl]-L-carnitine
	[(3R)-3-Hydroxydodecanoyl]-L-carnitine is an endogenous metabolite[1]. [1]. Hunter WG, et al. Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Failure With Preserved Versus Reduced Ejection Fraction: Evidence for Shared Metabolic Impairments in Clinical Heart Failure. J Am Heart Assoc. 2016;5(8):e003190. Published 2016 Jul 29.
T20193	L-Carnitine tartrate L-Carnitine L-tartrate,Carnipure tartrate
	L-Carnitine tartrate is a Carnitine/ Constituent of striated muscle and liver. It is used to treatment of hyperlipoproteinemias.
T21841	(±)-Hexanoylcarnitine chloride DL-Hexanoylcarnitine chloride	Others	Others
	(±)-Hexanoylcarnitine chloride 是一种脂肪酸代谢产物，能将脂肪酸分解成能够被身体利用的小分子化合物。(±)-Hexanoylcarnitine chloride 可通过大鼠骨骼肌毒性特异性从而作为一种生物标志物。
T22484	(±)-Propionylcarnitine chloride Propionyl-DL-carnitine chloride	Endogenous Metabolite	Metabolism
	(±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) 是一种短链酰基肉碱的混合物，可用作膳食补充剂，可用于研究慢性糖尿病。
T12356	Palmitoylcarnitine Palmitoyl DL-carnitine	Endogenous Metabolite	Metabolism
	Palmitoylcarnitine (Palmitoyl DL-carnitine) 是一种线粒体脂肪酸氧化中间体，可作为表面活性剂。
T13810	Palmitoylcarnitine chloride Palmitoyl DL-carnitine chloride	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) 是一种线粒体脂肪酸氧化中间体，可介导脂质内心脏保护。Palmitoylcarnitine chloride 通过消耗谷胱甘肽来消除结直肠癌细胞的存活，诱导癌细胞死亡，调节蛋白激酶 C βII 与其受体 RACK1 之间的相互作用。
T73752	Glutarylcarnitine lithium
	Glutarylcarnitine lithium 丙二酸尿症和 I 型戊二酸尿症的重要诊断代谢物。
T37299	L-Palmitoylcarnitine chloride
	Palmitoyl-L-carnitine is a naturally occurring long-chain acylcarnitine and the L-enantiomer of palmitoyl-DL-carnitine . In cells, palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 μM. In vivo, palmitoyl-L-carnitine increases intestinal absorption of the ant...
T15698	L-Palmitoylcarnitine	Others	Others
	L-Palmitoylcarnitine is a metabolite of fatty acid.
T29598	Acetylcarnitine arginyl amide ST-857,acetyl-L-carnitine arginine amide
	Acetylcarnitine arginyl amide is able to stimulate neurite outgrowth in a manner similar to that elicited by nerve growth factor (NGF). Neurite induction by this molecule requires de novo mRNA synthesis and is independent of the action of several common t
T19528	Propionylcarnitine Propionyl carnitine	Others	Others
	Propionylcarnitine (Propionyl carnitine) 是一种被广泛使用的膳食补充剂，有青光眼和难道破裂有关。
T73748	2-Methylbutyrylcarnitine
	2-Methylbutyrylcarnitine是一种存在于人体和动物血液及尿液中的脂肪酸代谢产物，通过丙酮酸羧化途径生成。在脂肪性肝炎(NASH)患者中，2-Methylbutyrylcarnitine的血浆水平较高，因此可用作代谢性疾病诊断的一个指标。
T31351	Decanoylcarnitine, (+)- (+)-Decanoylcarnitine
	Decanoylcarnitine, (+)- is a biochemical.
T22483	(±)-Octanoylcarnitine chloride	Others	Others
	(±)-Octanoylcarnitine chloride is a homolog of acetylcarnitine chloride.

化合物

[(3R)-3-Hydroxydodecanoyl]-L-carnitine

Cat.No: T37516

L-Carnitine tartrate

Cat.No: T20193

Synonym: L-Carnitine L-tartrate,Carnipure tartrate

(±)-Hexanoylcarnitine chloride

Cat.No: T21841

Synonym: DL-Hexanoylcarnitine chloride

Target: Others

(±)-Propionylcarnitine chloride

Cat.No: T22484

Synonym: Propionyl-DL-carnitine chloride

Target: Endogenous Metabolite

Palmitoylcarnitine

Cat.No: T12356

Synonym: Palmitoyl DL-carnitine

Target: Endogenous Metabolite

Palmitoylcarnitine chloride

Cat.No: T13810

Synonym: Palmitoyl DL-carnitine chloride

Target: PKC

Glutarylcarnitine lithium

Cat.No: T73752

L-Palmitoylcarnitine chloride

Cat.No: T37299

L-Palmitoylcarnitine

Cat.No: T15698

Target: Others

Acetylcarnitine arginyl amide

Cat.No: T29598

Synonym: ST-857,acetyl-L-carnitine arginine amide

Propionylcarnitine

Cat.No: T19528

Synonym: Propionyl carnitine

Target: Others

2-Methylbutyrylcarnitine

Cat.No: T73748

Decanoylcarnitine, (+)-

Cat.No: T31351

Synonym: (+)-Decanoylcarnitine

(±)-Octanoylcarnitine chloride

Cat.No: T22483

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0846	L-Carnitine L(-)-Carnitine,Levocarnitine,左旋肉碱	Endogenous Metabolite; Fatty Acid Synthase	Metabolism
	L-Carnitine (L(-)-Carnitine) 是一种人内源性分子，在人体内以蛋氨酸和赖氨酸为底物进行生物合成，并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A 转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。
T20123	L-Carnitine hydrochloride L-Carnitine chloride,LC 80,Levocarnitine chloride,(R)-Carnitine hydrochloride,LC-80,LC80
	Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. Carnitine is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It has also been used to allow the en
T19384	Isovalerylcarnitine	Apoptosis; Cysteine Protease	Apoptosis; Proteases/Proteasome
	Isovalerylcarnitine (3-methylbutyrylcarnitine) 是 L-亮氨酸分解代谢和异戊酸的积累产生的小分子化合物，也是一种具有选择性和有效性的钙蛋白酶 (calpain) 激活剂，可促使细胞凋亡，与异戊酸血症有关，可作为异戊酸血症的标志。
T19398	L-Octanoylcarnitine	Endogenous Metabolite	Metabolism
	L-Octanoylcarnitine 是存在于血浆中的活性辛酰肉碱，是一种乳腺癌的潜在生物标志物。
T19340	Glutarylcarnitine O-glutaroyl-L-carnitine	Endogenous Metabolite	Metabolism
	Glutarylcarnitine (O-glutaroyl-L-carnitine) 是大多数串联质谱新生儿筛查计划中监测的丙二酸尿症和谷草酸尿症 I 型的诊断代谢物。
T12295	Oleoylcarnitine Oleoyl-L-carnitine	Endogenous Metabolite	Metabolism
	Oleoylcarnitine (Oleoyl-L-carnitine) 抑制腺嘌呤核苷酸转位酶（AdNT）活性，ic50为14 μM。Oleoylcarnitine 是检测神经分裂的重要指标。
T13280	Valerylcarnitine VALERYL-L-CARNITINE	Endogenous Metabolite	Metabolism
	Valerylcarnitine (VALERYL-L-CARNITINE) 是一种短链脂肪酸，可用于研究 2 型糖尿病。
T15157	Dodecanoylcarnitine Lauroylcarnitine	Endogenous Metabolite	Metabolism
	Dodecanoylcarnitine（(-)-Lauroylcarnitine）和脂肪酸氧化紊乱有关，使用 Dodecanoylcarnitine 可使鲑鱼降钙素的通透性增加。
T14840	Butyrylcarnitine	Endogenous Metabolite	Metabolism
	Butyrylcarnitine 是血浆中的代谢物，是疾病引起异常代谢的指标，可用于诊断心力衰竭和胰腺囊肿。
T17048	Tetradecanoylcarnitine L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine	Endogenous Metabolite	Metabolism
	Tetradecanoylcarnitine (L-Myristoylcarnitine) 是一种酰基肉碱，参与长链脂肪酸的β-氧化,是极长链酰辅酶A脱氢酶缺乏症的一种潜在标记物。
T19564	Stearoylcarnitine Stearoyl-L-carnitine	Endogenous Metabolite	Metabolism
	Stearoylcarnitine (Stearoyl-L-carnitine) 是一种脂肪酯脂质分子，是一种人内源代谢产物，可作为早发型子痫前期和晚发性子痫前期的生物标志物。
T19391	L-Hexanoylcarnitine	Others	Others
	L-Hexanoylcarnitine is found to be associated with celiac disease, is an acylcarnitine.
T73764	L-Palmitoylcarnitine TFA
	L-Palmitoylcarnitine TFA 是一种长链酰基肉碱和脂肪酸代谢产物，在缺血期间积聚于肌膜并扰乱膜脂环境。L-Palmitoylcarnitine TFA 通过与Kir6.2的相互作用抑制KATP 通道活性，而不影响单通道电导。

天然产物

Cat.No: T0846

Synonym: L(-)-Carnitine,Levocarnitine,左旋肉碱

Target: Endogenous Metabolite, Fatty Acid Synthase

L-Carnitine hydrochloride

Cat.No: T20123

Synonym: L-Carnitine chloride,LC 80,Levocarnitine chloride,(R)-Carnitine hydrochloride,LC-80,LC80

Isovalerylcarnitine

Cat.No: T19384

Target: Apoptosis, Cysteine Protease

L-Octanoylcarnitine

Cat.No: T19398

Target: Endogenous Metabolite

Glutarylcarnitine

Cat.No: T19340

Synonym: O-glutaroyl-L-carnitine

Target: Endogenous Metabolite

Oleoylcarnitine

Cat.No: T12295

Synonym: Oleoyl-L-carnitine

Target: Endogenous Metabolite

Valerylcarnitine

Cat.No: T13280

Synonym: VALERYL-L-CARNITINE

Target: Endogenous Metabolite

Dodecanoylcarnitine

Cat.No: T15157

Synonym: Lauroylcarnitine

Target: Endogenous Metabolite

Butyrylcarnitine

Cat.No: T14840

Target: Endogenous Metabolite

Tetradecanoylcarnitine

Cat.No: T17048

Synonym: L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine

Target: Endogenous Metabolite

Stearoylcarnitine

Cat.No: T19564

Synonym: Stearoyl-L-carnitine

Target: Endogenous Metabolite

L-Hexanoylcarnitine

Cat.No: T19391

Target: Others

L-Palmitoylcarnitine TFA

Cat.No: T73764

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