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Search Results for " lag3 "

3

抑制剂 & 化合物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T82471	Encelimab
	Encelimab是一种抗LAG3抗体，能够阻断 LAG-3 与 MHC II 的交互作用并增强T细胞活性。在单独应用或与抗PD-1抗体结合时，Encelimab能有效减小A20细胞异种移植瘤小鼠模型中的淋巴瘤肿瘤体积。
T40211	eIF4E-IN-1 eIF4E-IN-1
	eIF4E-IN-1 (WO2021003194A1, compound Y), is a highly effective inhibitor of eIF4E, a key protein involved in immunosuppression. By targeting immune checkpoint proteins such as PD-1, PD-L1, LAG3, TIM3, and IDO, eIF4E-IN-1 functions to disrupt immune suppression and promote immune release in specific diseases such as cancer and infectious diseases.
T62927	HPK1-IN-22
	HPK1-IN-22 (compound ZYF0033) 是一种造血祖细胞激酶 1 (HPK1) 抑制剂，基于 MBP 蛋白的磷酸化抑制作用的 IC50小于 10 nM。HPK1-IN-22 能够减少 SLP76 (丝氨酸 376) 的磷酸化，促进抗癌免疫反应。HPK1-IN-22 可以抑制 4T-1 同基因小鼠模型中的肿瘤生长，增加 DC、NK 细胞和 CD107a+CD8+T 细胞的肿瘤内浸润，但会减少 T 细胞、PD-1+CD8+T 细胞、TIM-3+CD8+T 细胞和 LAG3+CD8+T 细胞的浸润。

化合物

Cat.No: T82471

Cat.No: T40211

Synonym: eIF4E-IN-1

Cat.No: T62927

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00321	LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated Lymphocyte activation gene 3 protein,CD223...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is P18627.
TMPJ-01421	LAG-3 Protein, Cynomolgus, Recombinant (hFc) LAG-3,Protein FDC,Lymphocyte activation ge...	Cynomolgus	HEK293 Cells
	LAG-3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90 KDa and the accession number is XP_005570011.1.
TMPK-00204	FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Hepassocin,Lag3 ligand,HP-041,LFIRE-1,HFRE...	Human	HEK293 Cells
	Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3.
TMPY-04730	LAG-3 Protein, Human, Recombinant (His) LAG-3,lymphocyte-activation gene 3	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa and the accession number is P18627-1.
TMPY-04939	LAG-3 Protein, Human, Recombinant LAG-3,lymphocyte-activation gene 3	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04528	LAG-3 Protein, Human, Recombinant (hFc) lymphocyte-activation gene 3,CD223,LAG...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.9 kDa and the accession number is P18627-1.
TMPY-04731	LAG-3 Protein, Human, Recombinant (mFc) lymphocyte-activation gene 3,CD223,LAG...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 72.6 kDa and the accession number is P18627-1.
TMPY-06931	LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated lymphocyte-activation gene 3,CD223,LAG...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 74.73 kDa and the accession number is NP_002277.4.
TMPY-05130	LAG-3 Protein, Human, Recombinant, Biotinylated lymphocyte-activation gene 3,CD223,LAG...	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-04612	LAG-3 Protein, Mouse, Recombinant (His) LAG-3,Ly66,lymphocyte-activation gene ...	Mouse	HEK293 Cells
	LAG-3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is Q61790.
TMPY-05746	LAG-3 Protein, Mouse, Recombinant lymphocyte-activation gene 3,LAG-3	Mouse	HEK293 Cells
	LAG-3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.25 kDa and the accession number is Q61790.
TMPY-04611	LAG-3 Protein, Mouse, Recombinant (hFc) lymphocyte-activation gene 3,Ly66,LAG-...	Mouse	HEK293 Cells
	LAG-3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.1 kDa and the accession number is Q61790.

重组蛋白

LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00321

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-01421

Species: Cynomolgus

Expression System: HEK293 Cells

FGL1 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00204

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04730

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant

Cat.No: TMPY-04939

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04528

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-04731

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06931

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05130

Species: Human

Expression System: HEK293 Cells

LAG-3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04612

Species: Mouse

Expression System: HEK293 Cells

LAG-3 Protein, Mouse, Recombinant

Cat.No: TMPY-05746

Species: Mouse

Expression System: HEK293 Cells

LAG-3 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04611

Species: Mouse

Expression System: HEK293 Cells

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