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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T22355 L-Thyroxine sodium

左旋甲状腺素钠,LT4 sodium,Levothyroxine sodium,L-T4 sodium

Thyroid hormone receptor(THR) Endocrinology/Hormones
L-Thyroxine sodium (LT4 sodium) 是一种合成的甲状腺激素,用于研究甲状腺功能减退症。DIO 酶能够将Levothyroxine 转化成具有生物活性的三碘甲状腺氨酸 (T3)。
T36383 L-Thyroxine-13C9,15N

L-Thyroxine-13C9,15N

L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse mode...
T15699 L-Thyroxine sodium salt pentahydrate

左旋甲状腺素钠五水合物,Sodium levothyroxine pentahydrate,Levothyroxine,L-甲状腺素钠五水合物

Thyroid hormone receptor(THR) Endocrinology/Hormones
L-Thyroxine sodium salt pentahydrate (Levothyroxine) 是一种合成的甲状腺激素,用于甲状腺功能减退症的研究。
T33576 N-Acetylthyroxine

N-Acetyl-L-thyroxine,N-Acetyl-T4

N-Acetylthyroxine is a kind of Thyroxine analogue for the treatment of diagnosing and treating diabetes.
T81983 Ketoprofen L-thyroxine ester

Ketoprofen L-thyroxine ester 作为一种活性前药,在大脑中贮存并能缓慢释放酮洛芬。
T82879 Biotin-hexanamide-(L-Thyroxine)

Biotin-hexanamide-(L-Thyroxine)为生物素化L-Thyroxine化合物。该化合物中的L-Thyroxine(即Levothyroxine;T4)作为一种合成甲状腺激素,广泛用于甲状腺功能减退症的研究中。
T1669 Liothyronine sodium

3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,三碘代甲状腺素钠盐,Sodium L-3,3',5-triiodothyronine,Cytomel

Thyroid hormone receptor(THR) Endocrinology/Hormones
Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) 是甲状腺激素,能够结合并激活 β1 甲状腺激素受体。

化合物

L-Thyroxine sodium
Cat.No: T22355
Synonym: 左旋甲状腺素钠,LT4 sodium,Levothyroxine sodium,L-T4 sodium
Target: Thyroid hormone receptor(THR)
L-Thyroxine-13C9,15N
Cat.No: T36383
Synonym: L-Thyroxine-13C9,15N
Target:
L-Thyroxine sodium salt pentahydrate
Cat.No: T15699
Synonym: 左旋甲状腺素钠五水合物,Sodium levothyroxine pentahydrate,Levothyroxine,L-甲状腺素钠五水合物
Target: Thyroid hormone receptor(THR)
N-Acetylthyroxine
Cat.No: T33576
Synonym: N-Acetyl-L-thyroxine,N-Acetyl-T4
Target:
Ketoprofen L-thyroxine ester
Cat.No: T81983
Synonym:
Target:
Biotin-hexanamide-(L-Thyroxine)
Cat.No: T82879
Synonym:
Target:
Liothyronine sodium
Cat.No: T1669
Synonym: 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,三碘代甲状腺素钠盐,Sodium L-3,3',5-triiodothyronine,Cytomel
Target: Thyroid hormone receptor(THR)
Cat. No. Product Name Target Signaling Pathways
T0864 L-Thyroxine

Levothyroxine,NSC 36397,L-甲状腺素,T4

Thyroid hormone receptor(THR); Endogenous Metabolite Endocrinology/Hormones; Metabolism
L-Thyroxine (NSC 36397) 是一种合成的甲状腺激素,用于甲状腺功能减退症的研究。在 DIO 酶作用下,L-Thyroxine (NSC 36397) 转化成具有生物特性的三碘甲状腺氨酸(T3)。
T36715 Tetrac

Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid

Apoptosis; EGFR Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tetrac (Tetraiodothyroacetic acid)是L-甲状腺素(T4)的衍生物,是一种甲状腺整合素受体拮抗剂。Tetrac通过阻断EGFR介导的结直肠癌细胞信号传导来诱导抗增殖。Tetrac 可阻断 T4 和 3,5,3'-triiodo-L-thyronine (T3)在细胞表面甲状腺素整合素 αvβ3 受体上的作用。Tetra 具有抗血管生成、抗肿瘤活性和促凋亡活性。

天然产物

L-Thyroxine
Cat.No: T0864
Synonym: Levothyroxine,NSC 36397,L-甲状腺素,T4
Target: Thyroid hormone receptor(THR), Endogenous Metabolite
Tetrac
Cat.No: T36715
Synonym: Tetraiodothyroacetic acid,3,3',5,5'-Tetraiodothyroacetic acid
Target: Apoptosis, EGFR
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