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Cat. No. Product Name Target Signaling Pathways
T0164 Oxaliplatin

L-OHP,奥沙利铂

DNA Alkylator/Crosslinker; DNA/RNA Synthesis; Autophagy Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Oxaliplatin (L-OHP) 是一种 DNA 烷化剂,一种 DNA 合成抑制剂。Oxaliplatin 会导致 DNA 交联损伤,阻止 DNA 复制和转录并导致细胞死亡。Oxaliplatin 可以诱导细胞自噬。
T71401 Oxaliplatin-d10

Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2....
T61870 (rel)-Oxaliplatin

(rel)-Oxaliplatin is a DNA synthesis inhibitor that induces DNA crosslinking damage, inhibits DNA replication and transcription, and stimulates apoptosis. This compound has applications in cancer research [1] [2] [3].

化合物

Oxaliplatin
Cat.No: T0164
Synonym: L-OHP,奥沙利铂
Target: DNA Alkylator/Crosslinker, DNA/RNA Synthesis, Autophagy
Oxaliplatin-d10
Cat.No: T71401
Synonym:
Target:
(rel)-Oxaliplatin
Cat.No: T61870
Synonym:
Target:
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