搜索结果

Search Results for " kaf "

抑制剂 & 化合物

天然产物

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T27400	Ganaplacide KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156
	Ganaplacide is an antimalarials with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. KAF156 showed antimalarial activity without evident safety concerns in a small number of adults with uncompli
T81917	Lorukafusp alfa hu14.18-IL2,EMD 273063,14.18 mAb
	Lorukafusp alfa（14.18 mAb; hu14.18-IL2）是一种由人源化14.18抗GD2抗体和IL210连接而成的免疫细胞因子。该化合物通过其hu14.18-IL2与肿瘤细胞表面的GD2结合，激活抗体依赖性细胞毒性（ADCC）和补体依赖性细胞毒性，以及与效应细胞上Fc受体结合并激活NK和T细胞的活性，从而显现出抗肿瘤效果。
T82449	Eramkafusp Alfa
	Eramkafusp Alfa为针对小鼠B淋巴细胞上CD20 (MS4A1) 抗原的人源化IgG1单克隆抗体。
T77052	Latikafusp
	Latikafusp (AMG 256)是一种靶向PD-1+细胞的双功能融合蛋白，整合了针对PD-1的抗体及IL-21突变蛋白，用于提供IL-21通路的刺激。通过启动和延长细胞毒性及记忆T细胞的活性，该蛋白质能够诱导抗肿瘤免疫反应，显示出对实体瘤研究的应用潜力。
T77091	Modakafusp alfa
	Modakafusp alfa (TAK-573) 是一种融合蛋白，由人源化抗CD38 IgG4 单克隆抗体和2个减毒IFNα2b分子组成。该化合物主要用于多发性骨髓瘤的研究。
T77169	Simlukafusp alfa
	Simlukafusp alfa (FAP-IL2v) 是一种免疫细胞因子，包括一种抗成纤维细胞活化蛋白 α (FAPα) 的抗体和一种只结合 IL-2Rβγ的 IL-2变体。Simlukafusp alfa 是一种人IgG1抗体。
T82508	Eciskafusp alfa	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	Eciskafusp alfa是一种针对程序性细胞死亡1(PDCD1，亦称PD-1)的顺式靶向IL2v免疫细胞因子。它优先选择抗原特异性干细胞样PD-1+ TCF-1+ CD8+ T细胞，并促使这些细胞分化成更高效的效应器细胞。Eciskafusp alfa主要用于癌症与慢性感染的研究领域。
T77112	Onfekafusp alfa
	Onfekafusp alfa（L19TNF）是一款将工程化的L19抗体scFv与人TNF融合所得的同源三聚体。该化合物主要应用于恶性胶质瘤的研究。
T82887	Bifikafusp alfa L19-IL2
	Bifikafusp alfa (L19-IL2) 是一种由人类L19抗体与细胞因子白介素2 (IL2) 结合而成的免疫融合蛋白，特异性针对纤维连接蛋白的EDB区域，并表现出抗癌活性。

化合物

Ganaplacide

Cat.No: T27400

Synonym: KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156

Target:

Lorukafusp alfa

Cat.No: T81917

Synonym: hu14.18-IL2,EMD 273063,14.18 mAb

Target: PD-1/PD-L1

Cat. No.	Product Name	Target	Signaling Pathways
T10327	Ankaflavin	PPAR	DNA Damage/DNA Repair; Metabolism
	Ankaflavin is isolated from Monascus-Fermented red rice and is a PPARγ agonist with anti-inflammatory activity. It shows the selective cytotoxic effect and induces cell death on cancer cells.

天然产物

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01023	Complement factor I Protein, Mouse, Recombinant (His) FIC3b-INA,I factor (complement),IF,C3B/C4B inactivator,C3BIN...	Mouse	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 66.39 kDa and the accession number is Q61129.
TMPK-00776	Complement factor I Protein, Human, Recombinant (His) FIC3b-INA,KAF,IF,CFI,I factor (complement),EC:3.4.2...	Human	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64.58 kDa and the accession number is P05156.