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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T79151 TLR8 agonist 6

TLR8 agonist6 (Compound A),具有EC50值为0.052 μM的TLR8激动特性,能够以EC50为0.031 μM的效力促进人PBMC中的IL-12p40生成。适用于抗病毒、抗感染、自身免疫和肿瘤相关研究领域。

化合物

TLR8 agonist 6
Cat.No: T79151
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN1787 Isomucronulatol 7-O-glucoside

Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷

Others Others
Isomucronulatol 7-O-glucoside 具有潜在的抗炎活性,在体外对 LPS 刺激产生的 IL-12 p40 表现出微弱的抑制作用。
T3848 7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside

Isomucronulatol 7-O-glucoside,7,2'-dihydroxy-3',4'-dimethoxyisoflavane-7-O-glucoside,黄芪异黄烷苷

Others Others
7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside (Isomucronulatol 7-O-glucoside) 是一种具有生物活性的异黄酮,分离自黄芪中。

天然产物

Isomucronulatol 7-O-glucoside
Cat.No: TN1787
Synonym: Isomucronulatol 7-O-beta-glucoside,黄芪紫檀烷苷,3-羟基-9,10-二甲氧基紫檀烷
Target: Others
7,2′-Dihydroxy-3′,4′-dimethoxyisoflavan 7-O-β-D-glucoside
Cat.No: T3848
Synonym: Isomucronulatol 7-O-glucoside,7,2'-dihydroxy-3',4'-dimethoxyisoflavane-7-O-glucoside,黄芪异黄烷苷
Target: Others
Cat. No. Product Name Species Expression System
TMPY-03516 IL-12B Protein, Mouse, Recombinant

Il-12p40,interleukin 12B,Il-12b,<...

Mouse HEK293 Cells
IL-12B Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.6 kDa and the accession number is P43432.
TMPY-03198 IL-12B Protein, Mouse, Recombinant (His)

Il-12p40,p40,interleukin 12B,Il

Mouse HEK293 Cells
IL-12B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is P43432.
TMPY-02350 IL-12 Protein, Mouse, Recombinant (His)

Il-12b,p35,IL-12p35,Ll12a,Il-12a,...

Mouse HEK293 Cells
IL-12 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.3 kDa and the accession number is P43431&P43432.
TMPY-02366 IL-12B Protein, Mouse, Recombinant (hFc)

Il-12p40,interleukin 12B,Il-12b,p...

Mouse HEK293 Cells
IL-12B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.8 kDa and the accession number is P43432.
TMPY-02351 IL-12 Protein, Mouse, Recombinant (His & hFc)

Il-12b,Il12p40,interleukin 12A,Ll...

Mouse HEK293 Cells
IL-12 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 85.9 kDa and the accession number is P43431&P43432.
TMPY-02349 IL-12 Protein, Mouse, Recombinant (hFc)

p40,Ll12a,IL-12p35,p35,白细胞介素,Il-12p40<...

Mouse HEK293 Cells
IL-12 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 111.5 kDa and the accession number is P43431&P43432.
TMPJ-00398 IL-12RB2 Protein, Mouse, Recombinant (hFc)

interleukin-12 receptor β-2 chain,IL-12RB2,interleu...

Mouse HEK293 Cells
The IL12 receptor complex, formed by IL12RB1 and IL12RB2, mediates the type I immune responses of various types of lymphocytes. Its ligand, IL12, is a heterodimeric cytokine composed of IL-12p35 and IL-12p40 subunits that are linked via disulfide bonds. Ligation of IL-12 to its receptor involves the binding of IL-12p35 to IL12RB1 and IL-12p40 to IL12RB2. This will result in the activation of tyrosine kinase 2 (TYK2), which is associated with the IL12RB1 chain and Janus kinase 2 (JAK2), which is ...
TMPJ-00363 IL-12RB1 Protein, Human, Recombinant (hFc)

IL-12R-β1,IL-12R-BETA1,IL-12 rece...

Human HEK293 Cells
Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL...

重组蛋白

IL-12B Protein, Mouse, Recombinant
Cat.No: TMPY-03516
Species: Mouse
Expression System: HEK293 Cells
IL-12B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03198
Species: Mouse
Expression System: HEK293 Cells
IL-12 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02350
Species: Mouse
Expression System: HEK293 Cells
IL-12B Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02366
Species: Mouse
Expression System: HEK293 Cells
IL-12 Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-02351
Species: Mouse
Expression System: HEK293 Cells
IL-12 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02349
Species: Mouse
Expression System: HEK293 Cells
IL-12RB2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00398
Species: Mouse
Expression System: HEK293 Cells
IL-12RB1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00363
Species: Human
Expression System: HEK293 Cells
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