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Targets Recommended: Others

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9537	N'-Nitro-D-arginine N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸	Others	Others
	N'-Nitro-D-arginine (N'-Nitro-D-arginine) 是一种砌块。
T14384	AZD8797 KAN-0440567,KAND567	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	AZD8797 (KAND567) 是一种可口服且具有选择性和有效性的人 CX3CR1 变构拮抗剂，对 CX3CR1 和 CXCR2 具有抑制作用，对SARS-CoV-2诱导的神经元损伤有潜在的保护作用，可防止癫痫发作后偏头痛模型大鼠痛觉过敏和小胶质细胞活化的恶化。

化合物

N'-Nitro-D-arginine

Cat.No: T9537

Synonym: N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸

Target: Others

AZD8797

Cat.No: T14384

Synonym: KAN-0440567,KAND567

Target: CXCR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04726	IL-8/CXCL8 Protein, Human, Recombinant (His) Interleukin-8,GCP1,MONAP,LECT,LYNAP,NAF,GCP-1,LUCT,...	Human	P. pastoris (Yeast)
	IL-8/CXCL8 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.8 kDa and the accession number is A0A024RDA5.
TMPY-00472	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) NAF,GCP1,NAP1,chemokine (C-X-C motif) ligand 8,Inte...	Human	E. coli
	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) is expressed in E. coli expression system. The predicted molecular weight is 8.5 kDa and the accession number is A0A024RDA5.
TMPY-00754	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) MONAP,MDNCF,NAP-1,白介素,NAP1,LUCT,chemokine (C-X-C motif) liga...	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) is expressed in HEK293 mammalian cells. The predicted molecular weight is 8 kDa and the accession number is A0A024RDA5.
TMPK-00480	IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His) GCP/IL-8 protein IV,MDNCF,CXCL8,G...	Cynomolgus	HEK293 Cells
	Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL-8 effects in gliomas are currently in progress while more-in-depth studies are needed to validate its biomarker role and elucidate the underlying molecular mechanisms.
TMPY-00755	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) chemokine (C-X-C motif) ligand 8,Interleukin-8<...	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDA5.
TMPY-00753	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc) LECT,MONAP,IL-8,LYNAP,白细胞介素,chemokine (C-X...	Human	HEK293 Cells
	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.6 kDa and the accession number is A0A024RDA5.
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,5'-nucleo...	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPJ-00582	PRG3 Protein, Human, Recombinant (His) Prepro-MBPH,Prepro-Major Basic Protein Homolog,Eosinophi...	Human	HEK293 Cells
	Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine an...
TMPH-03266	CHI3L1 Protein, Rat, Recombinant (His) Chi3l1,Cartilage glycoprotein 39,CGP-39,GP-39,Chiti...	Rat	E. coli
	Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mu...
TMPJ-00397	IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated CD217,IL17RA,interleukin 17 receptor A,IL1...	Human	HEK293 Cells
	CD217, also known as Interleukin-17 receptor A, is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F, it binds to IL17A with higher affinity than to IL17F and binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. It also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. The activation of IL17RA would lead to induction of expression of inflammatory chemokines...