Cat. No. | Product Name | Species | Expression System |
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TMPJ-01392 |
IL-1 beta/IL-1F2 Protein, Cavia porcellus, Recombinant (His)
IL-1 β,IL1B,IL-1 beta,In... |
Cavia porcellus | E. coli |
Interleukin-1 beta (IL1B) belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and... | |||
TMPY-04011 |
IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant
白介素,IL1-β,interleukin 1, beta,interleukin 1, β,... |
Rabbit | E. coli |
IL-1 beta/IL-1F2 Protein, Rabbit, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P14628. | |||
TMPK-00515 |
IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
Interleukin-1 β,IL-1 beta,IL1B, |
Cynomolgus | E. coli |
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The p... | |||
TMPK-00161 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)
Interleukin-1 beta,IL-1 β,IL-1β,IL |
Human | E. coli |
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi) is expressed in E. coli expression system with C-His-Avi tag. ... | |||
TMPK-00162 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
IL-1 β,IL-1β,IL-1 β/IL-1... |
Human | E. coli |
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with C... | |||
TMPH-03599 |
Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)
|
Streptococcus pyogenes | E. coli |
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO... | |||
TMPH-03598 |
Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)
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Streptococcus pyogenes | E. coli |
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO) is expressed in E. coli expression system with... | |||
TMPY-03983 |
CIRBP Protein, Human, Recombinant (His)
cold inducible RNA binding protein,CIRP |
Human | E. coli |
CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator.CIRBP can bind the 3 translated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for... | |||
TMPJ-00546 |
EFNA1 Protein, Human, Recombinant (hFc)
TNFAIP4,LERK1,Tumor Necrosis Factor α-Induced Protein 4,Imme... |
Human | HEK293 Cells |
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the... | |||
TMPJ-00909 |
IL-1RA Protein, Mouse, Recombinant
IL-1RN,IRAP,Interleukin-1 Receptor Antagonist Prote... |
Mouse | E. coli |
Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouse Il1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26% and 19% identity with its homologues IL-1 beta and I... | |||
TMPH-02613 |
ATF-5 Protein, Mouse, Recombinant (His & Myc)
Transcription factor ATFx,Transcription factor-like protein ... |
Mouse | E. coli |
Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters. Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation. Its transcrip... | |||
TMPJ-01100 |
UBE2V1 Protein, Human, Recombinant (His)
TRAF6-Regulated IKK Activator 1 Beta Uev1A,P/OKcl.19,TRAF6-R... |
Human | E. coli |
Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) is a member of the Ubiquitin-conjugating (E2) enzyme family. The E2 catalytic core domain of UBE2V1 lacks an active site cysteine residue, rendering it catalytically inactive on its own. However, in the cytoplasm UBE2V1 is able to form a catalytically active complex with UBE2N/Ubc13, which mediates the synthesis Lys63-linked Ubiquitin chains and is required for NF-kappa B activation. UBE2V1 is required for UBE2N (Ubc13)/UBE2V1 Complex-dependent Ly... | |||
TMPH-02671 |
Gasdermin-D Protein, Mouse, Recombinant (His & Myc)
|
Mouse | E. coli |
Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis.; Promotes pyroptosis in response to microbial infection and danger signals. Produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4/CASP11 in response to canon... | |||
TMPH-01502 |
Humanin Protein, Human, Recombinant (GST)
|
Human | E. coli |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation.... | |||
TMPH-01503 |
Humanin Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation.... |