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Search Results for " il-6r "
Targets Recommended: Interleukin

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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T9911 Tocilizumab

Interleukin Immunology/Inflammation
Tocilizumab 是抗人白细胞介素-6 受体 (IL-6R) 的中和抗体，能够阻碍 IL-6 与 IL-6R 的结合，进而抑制经典和反式信号。它可用于研究类风湿性关节炎，对重症 COVID-19 冠状病毒病方面的研究具有显著效果。
T77062 Levilimab

Levilimab (BCD-089)，一种全人源性抗IL-6R单克隆抗体，作为炎症缓解抗体用于类风湿研究。
T76878 Vobarilizumab

Vobarilizumab (ALX-0061) 是一种抗 IL-6R 单克隆抗体 (mAb) (Kd: 0.19 pM)。Vobarilizumab 由一个抗 IL-6R 结构域和一个抗人血清白蛋白结构域组成。Vobarilizumab 可用于炎症性自身免疫性疾病的研究，如类风湿性关节炎。
T35389 Sarilumab (anti-IL-6Rα)

IL Receptor Immunology/Inflammation
Sarilumab (anti-IL-6Rα)是人源anti-IL-6Rα单克隆抗体，与膜结合的和可溶性的IL-6Rα以高亲和力结合。MW: 144.13 KD。

化合物

Tocilizumab
Cat.No: T9911
Synonym:
Target: Interleukin
Levilimab
Cat.No: T77062
Synonym:
Target:
Vobarilizumab
Cat.No: T76878
Synonym:
Target:
Sarilumab (anti-IL-6Rα)
Cat.No: T35389
Synonym:
Target: IL Receptor
Species：
Human (7)
Rat (2)
Rhesus (2)
Canine (1)
Mouse (1)
Expression System：
HEK293 Cells (13)
Tag：
C-His (7)
C-His-Avi (2)
C-hFc (2)
C-Avi-6xHis (1)
Tag Free (1)
Cat. No. Product Name Species Expression System
TMPY-00864 IL-6R Protein, Human, Recombinant (His)

IL-6R-1,IL-6RA,IL

Human HEK293 Cells
IL-6R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is A0N0L5.
TMPY-05278 IL-6R Protein, Human, Recombinant (hFc)

IL-6R-1,CD126,gp80,IL6Q,IL

Human HEK293 Cells
IL-6R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the accession number is A0N0L5.
TMPY-01214 IL-6R Protein, Mouse, Recombinant (His)

MGC30256,IL-6R,Il6r,inte...

 Mouse HEK293 Cells
IL-6R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P22272.
TMPK-00289 IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi)

IL-6R subunit alpha,IL-6R

Human HEK293 Cells
The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6R alpha) and a signal-transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for high-affinity binding of IL-6 by the complex. Both components of the receptor complex, IL-6R alpha and gp130 have been cloned, sequenced, and expresse...
TMPY-05640 IL-6R Protein, Human, Recombinant, Biotinylated

IL6RQ,IL-6R,IL<...

 Human HEK293 Cells
IL-6R Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 67.1 kDa and the accession number is A0N0L5.
TMPY-06297 IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated

CD126,IL-6RA,IL6RA,I...

 Human HEK293 Cells
IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.80 kDa and the accession number is A0N0L5.
TMPJ-00291 IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated

IL-6R-α,IL-6R-alpha,Inte...

 Human HEK293 Cells
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an...
TMPK-00412 gp130/IL6ST Protein, Human, Recombinant (His)

gp130,CD130,IL-6 R beta,IL6ST,IL-...

 Human HEK293 Cells
gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. gp130/IL6ST Protein, Human, Recombinant (His) is expressed in H...
TMPK-00646 gp130/IL6ST Protein, Rhesus macaque, Recombinant (His)

IL-6 R β,gp130,IL6ST,IL-6R

Rhesus HEK293 Cells
gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. gp130/IL6ST Protein, Rhesus macaque, Recombinant (His) is expre...
TMPY-04187 IL-6R Protein, Rat, Recombinant (hFc)

interleukin 6 receptor

 Rat HEK293 Cells
IL-6R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.8 kDa and the accession number is A6J6I0.
TMPY-00135 IL-6R Protein, Canine, Recombinant (His)

interleukin 6 receptor

 Canine HEK293 Cells
IL-6R Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.8 kDa and the accession number is A0A8C0PF44.
TMPY-02560 IL-6R Protein, Rat, Recombinant (His)

interleukin 6 receptor

 Rat HEK293 Cells
IL-6R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is A6J6I0.
TMPY-04859 IL-6R Protein, Rhesus, Recombinant (His)

interleukin 6 receptor

 Rhesus HEK293 Cells
IL-6R Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is A0A5F8AUE5.

重组蛋白

IL-6R Protein, Human, Recombinant (His)
Cat.No: TMPY-00864
Species: Human
Expression System: HEK293 Cells
IL-6R Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05278
Species: Human
Expression System: HEK293 Cells
IL-6R Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01214
Species: Mouse
Expression System: HEK293 Cells
IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00289
Species: Human
Expression System: HEK293 Cells
IL-6R Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05640
Species: Human
Expression System: HEK293 Cells
IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06297
Species: Human
Expression System: HEK293 Cells
IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
Cat.No: TMPJ-00291
Species: Human
Expression System: HEK293 Cells
gp130/IL6ST Protein, Human, Recombinant (His)
Cat.No: TMPK-00412
Species: Human
Expression System: HEK293 Cells
gp130/IL6ST Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00646
Species: Rhesus
Expression System: HEK293 Cells
IL-6R Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-04187
Species: Rat
Expression System: HEK293 Cells
IL-6R Protein, Canine, Recombinant (His)
Cat.No: TMPY-00135
Species: Canine
Expression System: HEK293 Cells
IL-6R Protein, Rat, Recombinant (His)
Cat.No: TMPY-02560
Species: Rat
Expression System: HEK293 Cells
IL-6R Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-04859
Species: Rhesus
Expression System: HEK293 Cells
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