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Search Results for " il-1ra "
Targets Recommended: IκB/IKK Autophagy

2

抑制剂 & 化合物

6

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T0097 MRT67307

MRT67307 HCl

IκB/IKK; Autophagy Autophagy; NF-κB
MRT67307 是一种IKKε和TBK-1的双抑制剂,IC50分别为 160 和 19 nM。它抑制细胞自噬,也可抑制ULK1和ULK2,IC50分别为 45 和 38 nM。
T23028 MRT67307 HCl (1190378-57-4 free base)

MRT67307 HCl

Others Others
MRT67307 is an inhibitor for TBK1, IKKε , MARK1-4 and NUAK1 with IC50 value of 19, 160, 27-52 and 230nM , respectively [1]. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38nM, respectively [2]. Also, it is a salt inducible kinase (SIK) inhibitor with IC50 value of 250, 67 and 430nM for SIK1, SIK2 and SIK3, respectively.<br />SIKs prevent the formation of regulatory macrophages and their inhibition induces increasing in some markers of regulatory macrophages, such as IL-10 and oth...

化合物

MRT67307
Cat.No: T0097
Synonym: MRT67307 HCl
Target: IκB/IKK, Autophagy
MRT67307 HCl (1190378-57-4 free base)
Cat.No: T23028
Synonym: MRT67307 HCl
Target: Others
Cat. No. Product Name Species Expression System
TMPY-00853 IL-1RA Protein, Human, Recombinant

DIRA,IL1RA,interleukin <...

Human E. coli
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPY-00852 IL-1RA Protein, Human, Recombinant (hFc)

interleukin 1 receptor antagonist,MVCD4,IRA

Human HEK293 Cells
IL-1RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.8 kDa and the accession number is P18510-1.
TMPJ-00909 IL-1RA Protein, Mouse, Recombinant

IL-1RN,IRAP,Interleukin-1

Mouse E. coli
Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouse Il1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26% and 19% identity with its homologues IL-1 beta and I...
TMPY-05845 IL-1RA Protein, Cynomolgus, Recombinant (His)

interleukin 1 receptor antagonist

Cynomolgus E. coli
IL-1RA Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.63 kDa and the accession number is Q866R8.
TMPY-03081 IL-1RA Protein, Rat, Recombinant (hFc)

interleukin 1 receptor antagonist

Rat HEK293 Cells
IL-1RA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.8 kDa and the accession number is P25086.
TMPY-05837 IL-1RA Protein, Rat, Recombinant (His)

interleukin 1 receptor antagonist

Rat E. coli
IL-1RA Protein, Rat, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 19.01 kDa and the accession number is A6JSY4.

重组蛋白

IL-1RA Protein, Human, Recombinant
Cat.No: TMPY-00853
Species: Human
Expression System: E. coli
IL-1RA Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00852
Species: Human
Expression System: HEK293 Cells
IL-1RA Protein, Mouse, Recombinant
Cat.No: TMPJ-00909
Species: Mouse
Expression System: E. coli
IL-1RA Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05845
Species: Cynomolgus
Expression System: E. coli
IL-1RA Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03081
Species: Rat
Expression System: HEK293 Cells
IL-1RA Protein, Rat, Recombinant (His)
Cat.No: TMPY-05837
Species: Rat
Expression System: E. coli
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