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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76727 |
Teprotumumab
R 1507,HZN 001 |
TSH Receptor; IGF-1R | GPCR/G Protein; Tyrosine Kinase/Adaptors |
Teprotumumab 是一种阻断 IGF-1 受体 (IGF-1R) 的人单克隆抗体。Teprotumumab 与 IGF-1R 的细胞外 α-亚基结构域配体结合。Teprotumumab 抑制纤维细胞中的 TSH 和 IGF-1 作用。Teprotumumab 可降低 TSH 依赖性 IL-6 和 IL-8 的表达和 Akt 的磷酸化。Teprotumumab 可用于甲状腺相关眼病的研究。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01047 |
IL-1R1 Protein, Human, Recombinant (hFc)
IL-1R-α,IL-1 RI,IL |
Human | HEK293 Cells |
IL-1R1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63 kDa and the accession number is P14778. | |||
TMPY-01048 |
IL-1R1 Protein, Human, Recombinant (His)
IL-1R-α,IL-1R1,... |
Human | HEK293 Cells |
IL-1R1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is P14778. | |||
TMPY-03426 |
IL-1R1 Protein, Human, Recombinant
IL-1R-alpha,IL1R,IL<... |
Human | HEK293 Cells |
IL-1R1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.8 kDa and the accession number is P14778. |