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Targets Recommended: TSH Receptor IGF-1R

1

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76727 Teprotumumab

R 1507,HZN 001

TSH Receptor; IGF-1R GPCR/G Protein; Tyrosine Kinase/Adaptors
Teprotumumab 是一种阻断 IGF-1 受体 (IGF-1R) 的人单克隆抗体。Teprotumumab 与 IGF-1R 的细胞外 α-亚基结构域配体结合。Teprotumumab 抑制纤维细胞中的 TSH 和 IGF-1 作用。Teprotumumab 可降低 TSH 依赖性 IL-6 和 IL-8 的表达和 Akt 的磷酸化。Teprotumumab 可用于甲状腺相关眼病的研究。

化合物

Teprotumumab
Cat.No: T76727
Synonym: R 1507,HZN 001
Target: TSH Receptor, IGF-1R
Cat. No. Product Name Species Expression System
TMPY-01047 IL-1R1 Protein, Human, Recombinant (hFc)

IL-1R-α,IL-1 RI,IL

Human HEK293 Cells
IL-1R1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63 kDa and the accession number is P14778.
TMPY-01048 IL-1R1 Protein, Human, Recombinant (His)

IL-1R-α,IL-1R1,...

Human HEK293 Cells
IL-1R1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is P14778.
TMPY-03426 IL-1R1 Protein, Human, Recombinant

IL-1R-alpha,IL1R,IL<...

Human HEK293 Cells
IL-1R1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.8 kDa and the accession number is P14778.

重组蛋白

IL-1R1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01047
Species: Human
Expression System: HEK293 Cells
IL-1R1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01048
Species: Human
Expression System: HEK293 Cells
IL-1R1 Protein, Human, Recombinant
Cat.No: TMPY-03426
Species: Human
Expression System: HEK293 Cells
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