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Cat. No. | Product Name | Target | Signaling Pathways |
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T80586 |
Anti-Mouse IL-1a Antibody (ALF-161)
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Integrin | Cytoskeletal Signaling |
Anti-Mouse IL-1a Antibody 为针对小鼠IL-1a 的IgG1类免疫抑制单克隆抗体,源自Armenian Hamster。 | |||
T63873 | Anti-Aβ agent 1A | ||
Anti-Aβ agent 1A 是有效的抗淀粉样蛋白-β (amyloid-β) 剂。Anti-Aβ agent 1A 可明显抑制 LPS 诱导的 IL-1β、IL-6 和 TNF-α 水平,并能够利用线粒体途径减少 H2O2诱导的 SH-SY5Y 细胞凋亡,表现出抗氧化、抗炎、抗 Aβ 毒性和神经保护活性。Anti-Aβ agent 1A 能够用于研究阿尔兹海默症。 | |||
T76602 |
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
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(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) 作为一种CRF拮抗剂,能有效阻断IL-1a诱发的黄体生成素 (LH) 抑制作用。 | |||
T38160 |
STING Agonist 1a
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STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 . 1.Hou, H., Yang, R., Liu, X., et al.Discovery of triazoloquinoxaline as novel STING agonists via structure-based vir... |
Cat. No. | Product Name | Species | Expression System |
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TMPY-01738 |
IL-1 alpha/IL-1A Protein, Mouse, Recombinant
interleukin 1, α,IL-1 α/IL1A,inte... |
Mouse | E. coli |
IL-1 alpha/IL-1A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is P01582. | |||
TMPY-00854 |
IL-1 alpha/IL-1A Protein, Human, Recombinant
IL-1F1,interleukin 1, α,interleukin 1, alpha,白介素, |
Human | HEK293 Cells |
IL-1 alpha/IL-1A Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18 kDa and the accession number is P01583. | |||
TMPY-06981 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
interleukin 1 α,IL1,白介素,IL-1F1,IL... |
Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage... | |||
TMPK-00920 |
IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)
IL-1A,白介素,IL-1 alpha,Interleukin-... |
Cynomolgus | HEK293 Cells |
The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases. | |||
TMPJ-00162 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc)
Hematopoietin-1,Interleukin-1 Alpha,白介素,IL-1 α,... |
Human | HEK293 Cells |
IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 54 KDa and the accession number is P01583. | |||
TMPY-05836 |
IL-1 alpha/IL-1A Protein, Rat, Recombinant
interleukin 1, alpha,IL-1 α/IL1A,... |
Rat | E. coli |
IL-1 alpha/IL-1A Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.80 kDa and the accession number is P16598. | |||
TMPJ-00161 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated
Hematopoietin-1,IL-1 α,IL-1 Alpha,白细胞介素,In... |
Human | E. coli |
IL-1 alpha/IL-1A Protein, Human, Recombinant (Avi), Biotinylated is expressed in E. coli expression system with C-Avi tag. The predicted molecular weight is 19 KDa and the accession number is P01583. | |||
TMPK-01378 |
IL-12B Protein, Cynomolgus, Recombinant (His)
CLMF2,NKSF2,CLMF,CLMF p40,IL-12B,IL-12 sub... |
Cynomolgus | HEK293 Cells |
Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin‑related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells and tumor necrosis factor‑like ligand 1A (TL1A), to prevent their effects. Recent studi... | |||
TMPJ-00226 |
SLAMF1 Protein, Mouse, Recombinant (His)
signaling lymphocytic activation molecule,SLAM famil |
Mouse | HEK293 Cells |
Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been... |