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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38105 |
Ixekizumab
LY2439821 |
IL Receptor; Interleukin | Immunology/Inflammation |
Ixekizumab (LY2439821) 是一种人源化 IgG4 单克隆抗体,可选择性结合和中和白细胞介素 IL-17A ,Kd 值<3 pM。Ixekizumab 科阻断 IL-17A 与 IL-17RA 的结合,但不与其他 IL-17 家族成员结合。Ixekizumab 用于治疗中重度斑块型银屑病、银屑病关节炎和牛皮癣。 | |||
T71573 |
STK630921
|
||
STK630921 is a blocker of IL-17A binding to the IL-17A receptor (IL-17RA). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01371 |
IL-17RA Protein, Human, Recombinant (His)
CANDF5,CD217,CDw217,IL-17 |
Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is Q96F46-1. | |||
TMPK-00405 |
IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated
IL-7R-alpha,IL-7R,ILRA,<... |
Human | HEK293 Cells |
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22. | |||
TMPY-05430 |
IL-17RA Protein, Human, Recombinant (hFc)
hIL-17R,interleukin 17 receptor A... |
Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.2 kDa and the accession number is Q96F46-1. | |||
TMPY-05119 |
IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated
interleukin 17 receptor A,hIL-17R... |
Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 61.6 kDa and the accession number is Q96F46-1. | |||
TMPY-05120 |
IL-17RA Protein, Human, Recombinant (His), Biotinylated
IL-17RA,CD217,hIL |
Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.9 kDa and the accession number is Q96F46-1. | |||
TMPY-06390 |
IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated
interleukin 17 receptor A,IL17R,C... |
Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 61.99 kDa and the accession number is Q96F46-1. | |||
TMPY-06391 |
IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated
CANDF5,CDw217,interleukin 17 receptor A,h<... |
Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 36.71 kDa and the accession number is Q96F46-1. | |||
TMPY-03557 |
IL-17RA Protein, Mouse, Recombinant (hFc)
Il17r,VDw217,Cdw217,inte... |
Mouse | HEK293 Cells |
IL-17RA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.3 kDa and the accession number is Q60943. | |||
TMPY-02996 |
IL-17RA Protein, Rat, Recombinant (His)
interleukin 17 receptor A |
Rat | HEK293 Cells |
IL-17RA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.1 kDa and the accession number is D4A740. | |||
TMPY-04842 |
IL-17RA Protein, Rhesus, Recombinant (His)
interleukin 17 receptor A |
Rhesus | HEK293 Cells |
IL-17RA Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accession number is XP_001102483.2. | |||
TMPY-03910 |
IL-17RA Protein, Rat, Recombinant (hFc)
interleukin 17 receptor A |
Rat | HEK293 Cells |
IL-17RA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 59.7 kDa and the accession number is D4A740. | |||
TMPY-03214 |
IL-17RA Protein, Rhesus, Recombinant (hFc)
interleukin 17 receptor A |
Rhesus | HEK293 Cells |
IL-17RA Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.3 kDa and the accession number is XP_001102483.1. | |||
TMPY-01849 |
IL-17RA Protein, Mouse, Recombinant (His)
Il17r,AW538159,interleukin 17 rec... |
Mouse | HEK293 Cells |
IL-17RA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.8 kDa and the accession number is Q60943. | |||
TMPJ-00397 |
IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated
CD217,IL17RA,interleukin... |
Human | HEK293 Cells |
CD217, also known as Interleukin-17 receptor A, is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F, it binds to IL17A with higher affinity than to IL17F and binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. It also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. The activation of IL17RA would lead to induction of expression of inflammatory chemokines... | |||
TMPK-00055 |
IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated
白介素,IL-17E,IL-25,IL1... |
Human | HEK293 Cells |
IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/IL-17RA complex, IL-25 induces downstream signaling responses in epithelial cells and type 2 lymphocytes, which initiates, propagates, and sustains type 2 immunity. The function of IL-25 in allergic diseases such as asthma has been well established, and now also is extended to diseases such as inflammatory bowel disease and cancer. |