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Targets Recommended: Apoptosis Epigenetic Reader Domain PLK

1

抑制剂 & 化合物

6

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T6173 BI 2536

4-[[(7R)-8-环戊基-7-乙基-5,6,7,8-四氢-5-甲基-6-氧代-2-喋啶基]氨基]-3-甲氧基-N-(1-甲基-4-哌啶基)苯甲酰胺

Apoptosis; Epigenetic Reader Domain; PLK Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic
BI 2536 一种是PLK1和BRD4的双抑制剂,IC50分别为 0.83 和 25 nM。它抑制 IFNB 干扰素 β 基因转录。

化合物

BI 2536
Cat.No: T6173
Synonym: 4-[[(7R)-8-环戊基-7-乙基-5,6,7,8-四氢-5-甲基-6-氧代-2-喋啶基]氨基]-3-甲氧基-N-(1-甲基-4-哌啶基)苯甲酰胺
Target: Apoptosis, Epigenetic Reader Domain, PLK
Cat. No. Product Name Species Expression System
TMPY-03467 IFN-beta Protein, Mouse, Recombinant

Ifb,IFN-β,interferon, beta 1, fibroblast,干扰素,IFNB,I...

Mouse HEK293 Cells
IFN-beta Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.3 kDa and the accession number is P01575.
TMPY-03145 IFN-beta Protein, Human, Recombinant

IFN-β,interferon, β1, fibroblast,IFNB,IFB,IFF,Inter...

Human CHO Cells
IFN-beta Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 20 kDa and the accession number is P01574.
TMPY-00831 IFN-beta Protein, Human, Recombinant (hFc)

IFNB,IFN-β,Interferon beta,interferon, beta 1, fibr...

Human HEK293 Cells
IFN-beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is A0A7R8GV38.
TMPY-00863 IL-6 Protein, Human, Recombinant

BSF2,白细胞介素,HSF,IL-6,IFNB2,interleukin 6,HGF,Interle...

Human E. coli
IL-6 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 20.95 kDa and the accession number is P05231.
TMPY-02456 IFN-beta Protein, Mouse, Recombinant (hFc)

Ifb,interferon, β1, fibroblast,IFN-β,干扰素,interferon, beta 1,...

Mouse HEK293 Cells
IFN-beta Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is P01575.
TMPK-00101 IL-6 Protein, Cynomolgus, Recombinant (His)

CDF,BSF-2,白介素,IL6,HGF,白细胞介素,Interleukin-6,HSF,MGI-2A,IFN-β-2...

Cynomolgus HEK293 Cells
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein.

重组蛋白

IFN-beta Protein, Mouse, Recombinant
Cat.No: TMPY-03467
Species: Mouse
Expression System: HEK293 Cells
IFN-beta Protein, Human, Recombinant
Cat.No: TMPY-03145
Species: Human
Expression System: CHO Cells
IFN-beta Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00831
Species: Human
Expression System: HEK293 Cells
IL-6 Protein, Human, Recombinant
Cat.No: TMPY-00863
Species: Human
Expression System: E. coli
IFN-beta Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02456
Species: Mouse
Expression System: HEK293 Cells
IL-6 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00101
Species: Cynomolgus
Expression System: HEK293 Cells
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