5
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11619 |
IDO-IN-5
NLG-1489 |
IDO | Metabolism |
IDO-IN-5 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM). | |||
T11901 |
IDO1-IN-5
|
IDO; Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
IDO1-IN-5 是可透过血脑屏障的、选择性的IDO1抑制剂,能够与缺乏血红素的 apo-IDO1 结合,但无法与成熟血红素的 IDO1 结合。 | |||
T12801 |
(S)-IDO1-IN-5
|
Others | Others |
(S)-IDO1-IN-5 is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL(IC50 value less than 1.5 µΜ). | |||
T12668 |
(Rac)-IDO1-IN-5
|
Others | Others |
(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5, a potent, selective, and brain-penetrating inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity. It specifically binds to apo-IDO1, which lacks heme, instead of mature heme-bound IDO1. | |||
T62130 | IDO-IN-16 | ||
IDO-IN-16 (compound 5) 是一种 IDO 抑制剂 (IC50: 36 nM)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5S0053 |
Coptisine
黄连碱,Coptisin |
Indoleamine 2,3-Dioxygenase (IDO) | Metabolism |
Coptisine (Coptisin) 是一种从黄连中分离到的生物碱,是非竞争性的IDO 抑制剂,Ki=为 5.8 μM,IC50=6.3 μM。 |