3
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27018 |
CID21480113
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CID21480113, an antibacterial agent, is effective in treating dapsone resistant leprosy. | |||
T61802 |
AK-778-XXMU
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Others | Others |
AK-778-XXMU 是一种 ID2 拮抗剂, KD值为 129 nM。AK-778-XXMU 具有潜在的抗肿瘤抗癌活性,可用于研究神经胶质瘤。 | |||
T79546 |
BMP agonist 1
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BMP agonist 1 (compound 2 b) 是一种作用于骨形态发生蛋白 (BMP) 的小分子激动剂。该化合物能在C2C12细胞中与BMP协同作用,诱导其分化,其机制高度依赖BMP的活性信号传递路径。此外,BMP agonist 1 通过抑制GSK3β和增强β-catenin信号的表达,进而共同调控了Id2和Id3基因的表达。这种化合物主要用于研究骨骼相关疾病及损伤。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1727 |
Helichrysetin
4,2',4'-三羟基-6'-甲氧基查耳酮,蜡菊亭 |
Apoptosis; HIV Protease | Apoptosis; Microbiology/Virology; Proteases/Proteasome |
Helichrysetin 是从豆蔻果实中分离出的一种天然产物,是一种 DNA 结合抑制剂,可抑制原位导管癌DCIS 的形成。它抑制细胞生长,可诱导 A549 细胞凋亡。 | |||
TN4168 | Grifolin | Others | Others |
Grifolin has anti-cancer effects, it induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways; it enhances the differentiation and proliferation of oligodendrocyte precurs |