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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2968L |
Hyodeoxycholic acid sodium salt
Sodium hyodeoxycholate,HDCA sodium |
Others | Others |
Hyodeoxycholic acid sodium salt is a natural secondary bile acid. It improves high-density lipoprotein function, reduces farnesoid X receptor antagonist bile acids, and induces strong cytotoxicity, apoptosis, and IL-8 synthesis. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37770 |
Taurohyodeoxycholic acid
|
Others | Others |
Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats.2Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats.3THDCA also reduces myeloperoxidase activity, expressi... | |||
T2968 |
Hyodeoxycholic acid
NSC 60672,猪去氧胆酸,α-Hyodeoxycholic Acid,HDCA |
FXR; Endogenous Metabolite; GPCR19 | GPCR/G Protein; Metabolism |
Hyodeoxycholic acid (NSC 60672) 是由肠道菌群在小肠中形成的次级胆汁酸,是TGR5(GPCR19)的激动剂, CHO 细胞中的EC50=31.6 µM。它已用于研究高胆固醇血症的治疗。 |