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Search Results for " hsp72 "

Targets Recommended: HSP

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T14905	CCT251236	HSP	Cytoskeletal Signaling; Metabolism
	CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen. It inhibits HSF1-mediated HSP72 induction (IC50: 19 nM).
T3515	TRC051384 HCl	HSP	Cytoskeletal Signaling; Metabolism
	TRC051384 HCl 是热休克蛋白 Hsp70 的诱导剂，可激活热休克因子-1 并增强神经元和神经胶质细胞中 Hsp72 的表达。
T2444	KNK437 Heat Shock Protein Inhibitor I	HSP	Cytoskeletal Signaling; Metabolism
	KNK437 (Heat Shock Protein Inhibitor I) 是一种 HSP 抑制剂，抑制 HSP40，HSP70 和 HSP105 的活化。
T3527	TRC051384 TRC 051384	HSP	Cytoskeletal Signaling; Metabolism
	TRC051384 是一种热休克蛋白70 (HSP70) 诱导剂，可减少中风相关的神经元损伤并增加短暂性缺血性中风大鼠模型的存活率，激活热休克因子-1 并导致分子伴侣和抗炎活性升高，增强神经元和神经胶质细胞中 Hsp72 的表达。
T36865	Heat Shock Protein Inhibitor II
	Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hsp72 synthesis in vivo and reduces thermotolerance of tumors in SCC VII tumor-containing mice. At 100 μM, it inhibits the development of thermotolerance in COLO 320 DM cells. Inhibition of Hsp70 with Hsp inhibitor II in combination with amphotericin B increases susceptibility of A...
T68760	Luminespib mesylate
	Luminespib, also known as AUY-922, NVP-AUY922, VER52296, is a derivative of 4,5-diarylisoxazole and a third-generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock protein 72 (Hsp72) in a wide range of human tumor cell lines.

化合物

Synonym: Heat Shock Protein Inhibitor I

Target: HSP

TRC051384

Cat.No: T3527

Synonym: TRC 051384

Target: HSP

Heat Shock Protein Inhibitor II

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02443	HSP70 Protein, Human, Recombinant (His) heat shock 70kDa protein 1A,HSP70-1,HSP70I...	Human	Baculovirus Insect Cells
	HSP70 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 72.2 kDa and the accession number is A8K5I0.
TMPY-06091	HSP70 Protein, Mouse, Recombinant (His) Hsp70-3,Hsp72,hsp68,...	Mouse	HEK293 Cells
	HSP70 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.5 kDa and the accession number is Q3TU85.