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9

抑制剂 & 化合物

1

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T65776	Fmoc-Ser(HPO3Bzl)-OH
	Fmoc-Ser(HPO3Bzl)-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65776，CAS号为 158171-14-3。
T2430	HPOB	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	HPOB 是一种高选择性HDAC6抑制剂，IC50为 56 nM，其选择性是其他 HDAC 的 30 倍以上。它提高 DNA 损伤抗癌药物在转化细胞中的有效性。
T37394	13(S)-HpOTrE
	13(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced in soybeans by the action of soybean LO-2 on esterified α-linolenic acid.[1] Incubation of soybean seedling biomembranes with soybean LO-2 catalyzes the formation of both 9- and 13-HpOTrE in a molar ratio of 10:1.1 In plants, 13(S)-HpOTrE can be metabolized by the hydroperoxide lyase pathway producing aldehyde and oxoacid fragments, or by the hydroperoxide dehydratase pathway producing jasmonic acid.[2],[3],[4] Treatment of to...
T41375	(±)13-HpODE
	(±)13-HpODE 在生命科学相关研究中具有广泛的应用。
T37867	9(S)-HpOTrE
	9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in the formation of 9,16-dihydroperoxy acid. The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to oc...
T37866	9(S)-HpODE
	9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid.
T37395	13(S)-HpOTrE(γ)
	13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid. Further action of soybean LO-1 converts 13(S)-HpOTrE(γ) to all four isomers of 6,13-DiHOTrE. At concentrations greater than 100 μM, 13(S)-HpOTrE(γ) inhibits the activity of soybean LO-1.
T37393	13(S)-HpODE
	13(S)-HpODE is produced by the oxidation of linoleic acid by lipoxygenase-1 (LO-1) in many plants including soybean, flaxseed, apples, and tea leaves,1,2 and by 15-LO in mammals.3 In plants, 13(S)-HpODE is the preferred substrate for the garlic bulb divinyl ether synthase.4 In mammalian tissues, 13(S)-HpODE is generally reduced to 13(S)-HODE，a compound which exhibits many biological activities.3 A direct action for 13(S)-HpODE has been demonstrated in Syrian hamster embryo cells where it stimula...
T40327	Tetra-N-acetylchitotetraose
	Tetra-N-acetylchitotetraose, a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia, stimulates plant defense systems. Moreover, it serves as a substrate for the CO deacetylase nodulation protein NodB in Rhizobium leguminosarum.

化合物

Fmoc-Ser(HPO3Bzl)-OH

Cat.No: T65776

Cat.No: T2430

Target: Apoptosis, HDAC

Cat.No: T37394

Cat.No: T41375

Cat.No: T37867

Cat.No: T37866

13(S)-HpOTrE(γ)

Cat.No: T37395

Cat.No: T37393

Tetra-N-acetylchitotetraose

Cat.No: T40327

Cat. No.	Product Name	Target	Signaling Pathways
T36560	(±)9-HpODE
	(±)9-HpODE is a racemic mixture of the fatty acid hydroperoxide product (9(S)-HpODE) formed from lipoxygenase action on linoleic acid. It shows antimicrobial activity against various fungal and bacterial pathogens and thus may play a role in plant defense. In mammalian species, monocyte-induced oxidization of LDL generates significant amounts of esterified 9-HpODE, which is rapidly reduced to 9-HODE.

天然产物

Cat.No: T36560

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00368	ALR Protein, Human, Recombinant (His) HPO,ERV1,HERV1,ALR,HSS,HPO2,growth factor,...	Human	HEK293 Cells
	Alterations in GFER gene have been associated with progressive mitochondrial myopathy, congenital cataracts, hearing loss, developmental delay, lactic acidosis and respiratory chain deficiency in 3 siblings born to consanguineous Moroccan parents by homozygosity mapping and candidate gene approach. Using homozygosity mapping, we discovered that a mutation in the GFER gene causes an infantile mitochondrial disorder.
TMPJ-01020	GFER Protein, Human, Recombinant (His) Augmenter of liver regeneration,FAD-linked sulfhydryl oxidas...	Human	E. coli
	GFER is a hepatotrophic growth factor and flavin-linked sulfhydryl oxidase which belongs to the Erv1/ALR family of proteins. GFER is widely expressed in various human tissues. They are two isoforms of this protein. Isoform 1 could regenerate the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ER...
TMPH-01662	Merlin Protein, Human, Recombinant (His)	Human	E. coli
	Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppress...

重组蛋白

ALR Protein, Human, Recombinant (His)

Cat.No: TMPY-00368

Species: Human

Expression System: HEK293 Cells

GFER Protein, Human, Recombinant (His)

Cat.No: TMPJ-01020

Species: Human

Expression System: E. coli

Merlin Protein, Human, Recombinant (His)

Cat.No: TMPH-01662

Species: Human

Expression System: E. coli

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