Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10603 |
BRD-6929
|
HIV Protease; HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome |
BRD-6929 是一种选择性的脑渗透性的HDAC1和HDAC2抑制剂 ,IC50值为 1 和 8 nM。它对 HDAC1 和 HDAC2 有高亲和力,Ki 值为 0.2 和 1.5 nM。它可研究情绪相关行为。 | |||
T5347 |
CXD101
CXD-101 |
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
CXD101 是一种选择性和具有口服活性的 I 类HDAC 抑制剂,有抗肿瘤活性,对HDAC1、HDAC2和HDAC3的IC50分别为 63、570 和 550 nM。 | |||
T26355 |
ZYJ-34c
ZYJ 34c,ZYJ34c |
||
ZYJ-34c is a potent oral antitumor activities histone deacetylase inhibitor (HDACi). | |||
T71917 |
FFK29
|
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FFK29 is a synthetic class II HDACi (Histone deacetylase inhibitors) which have have recently emerged as novel therapeutic options for treating various protozoan and parasitic diseases. While these HDACi demonstrated a negligible effect on the viability of mature cysts, Acanthamoeba encystation was significantly inhibited by these HDACi. In conclusion, these synthetic HDACi demonstrated potent amoebicidal effects and inhibited the growth and encystation of Acanthamoeba, thus highlighting their e... | |||
T26354 |
ZYJ-25e
ZYJ 25e |
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ZYJ-25e is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities. | |||
T26356 |
ZYJ-34v
|
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ZYJ-34v is an oral histone deacetylase inhibitor (HDACi) with potent antitumor activities. | |||
T62041 | XP5 | ||
XP5 是一种有效的、具有口服活性的HDAC6抑制剂(IC50= 31 nM)。XP5高效抑制各种癌细胞系(包括抗 HDACi 的 YCC3/7 胃癌细胞)的增殖 (IC50=0.16-2.31 μM)。 | |||
T70190 |
Tinostamustine HCl
|
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Tinostamustine, also known as EDO-S101, is an alkylatlng histone-deacetylase inhibitor (HDACi) fusion molecule. EDO-S101 is a functional pan-histone-deacetylase inhibitor and is assumed to potentiate the alkylating activity of the compound and/or may help to overcome resistance to other therapeutic agents. | |||
T61209 | HDAC-IN-27 | ||
HDAC-IN-27 是一种有效的口服活性HDACI 类选择性抑制剂,对 HDAC1-3 的 IC50值范围为 0.43 至 3.01 nM。抗急性髓系白血病 (AML) 活性。 |