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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T78360	Glyceraldehyde phosphate dehydrogenase GAPDH,G3PDH,GADPH
	Glyceraldehyde phosphate dehydrogenase是一种酶，既是抗胸腺细胞剂也是抗凋亡剂的靶点，它负责催化过羟基自由基对还原型烟酰胺腺嘌呤二核苷酸（NADH）的链氧化反应。
T77332	TV 3279	BCL; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling
	TV 3279是一种新型ChE-MAI 抑制剂，神经保护特性取决于它们诱导抗凋亡蛋白PKC、Bcl-2、Bcl-x 和SOD 的能力，并阻止促凋亡酶甘油醛磷酸脱氢酶在PC-12和神经母细胞瘤细胞中的核易位。
T37521	DL-Glyceraldehyde 3-phosphate 3-Phosphoglyceraldehyde,DL-甘油醛3-磷酸
	DL-Glyceraldehyde-3-phosphate (GADP) is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. In glycolysis, it can be derived from fructose 1,6-bisphosphate by fructose bisphosphate aldolase in a reaction that also produces dihydroxyacetone phosphate (DHAP). Triose phosphate isomerase reversibly converts DHAP to GADP. GADP is processed to 1,3-bisphosphoglycerate by glyceraldehyde phosphate dehydrogenase and NAD+.
T72879	Misetionamide
	Misetionamide，一种恶噻嗪类口服化合物，作为甘油醛-3-磷酸脱氢酶 (GAPDH) 抑制剂，展现出抗肿瘤活性，适用于癌症研究。
T10966	DC-5163	Others	Others
	DC-5163 is a potent inhibitor of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with IC50 of 176.3 nM and Kd of 3.192 μM. DC-5163 selectively inhibits cancer cell proliferation and induces apoptosis, and partially inhibits the glycolysis pathway.
T80931	Tri-valine NSC 35938
	Tri-valine (NSC 35938) 为多肽类化合物，可从肌酸激酶 (Creatine kinase)、β-烯醇化酶、三磷酸异构酶 (Triosephosphate isomerase) 及甘油醛 3-磷酸脱氢酶中分离得到。

化合物

Glyceraldehyde phosphate dehydrogenase

Cat.No: T78360

Synonym: GAPDH,G3PDH,GADPH

DL-Glyceraldehyde 3-phosphate

Cat.No: T37521

Synonym: 3-Phosphoglyceraldehyde,DL-甘油醛3-磷酸

Synonym: NSC 35938

Target:

Cat. No.	Product Name	Target	Signaling Pathways
TN4578	Monomethyl kolavate	Antifection	Microbiology/Virology
	Monomethyl kolavate is a power Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) inhibitor, with an IC50 value of 12uM.