Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11487 |
Fiboflapon
GSK2190915,AM-803 |
FLAP | Immunology/Inflammation |
Fiboflapon (GSK2190915) 是一种可口服且具有有效性 5-脂氧合酶激活蛋白 (FLAP) 抑制剂,结合 FLAP 的效价为 2.9 nM,对人血中 LTB4 有抑制作用, IC50 值为 76 nM。 | |||
T11487L |
Fiboflapon sodium
GSK2190915 sodium salt,AM-803 sodium |
LTR | Immunology/Inflammation |
Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood. |