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3

抑制剂 & 化合物

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天然产物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T40115 GAD65 (206-220)

GAD65 (206-220)

GAD65 (206-220) is a synthetic peptide derived from glutamic acid decarboxylase (GAD) 65, specifically corresponding to residues 180-188. It is known that GAD65 interacts with I-Ag7 MHC class II molecules and is a significant pancreatic antigen that self-reactive T cells target in type I diabetes mellitus.
T82354 GAD65 (524-543)

GAD65 (524-543) 是具有生物活性的肽,属于谷氨酸脱羧酶 65 (GAD65) 氨基酸片段 524-543。作为胰岛抗原的关键片段之一,该肽在自发性自身免疫性糖尿病非肥胖糖尿病 (NOD) 小鼠模型中,可诱导增殖性 T 细胞反应。GAD65 (524-543) 对T细胞克隆BDC2.5具有特异性刺激作用,但可能存在亲和力较低的问题。此外,p524-543免疫可增强NOD小鼠对通过BDC2.5 T细胞过继转移诱导的1型糖尿病的敏感性。
T80218 GAD65(247-266) epitope TFA

GABA Receptor Membrane transporter/Ion channel; Neuroscience
GAD65(247-266) epitope TFA 为T细胞表位,与I-Ag7(I型糖尿病相关分子)竞争性结合,亲和力较低。该表位源自胰岛抗原,GAD65 是谷氨酸脱羧酶 65,涉及将谷氨酸转换为γ-氨基丁酸(GABA)。

化合物

GAD65 (206-220)
Cat.No: T40115
Synonym: GAD65 (206-220)
Target:
GAD65 (524-543)
Cat.No: T82354
Synonym:
Target:
GAD65(247-266) epitope TFA
Cat.No: T80218
Synonym:
Target: GABA Receptor
Cat. No. Product Name Target Signaling Pathways
T5739 Paederosidic acid

鸡屎藤苷酸,异戊二酸 紫草酸

Apoptosis; BCL Apoptosis
Paederosidic acid 是从鸡矢藤分离出的一种天然产物,通过诱导线粒体介导的凋亡抑制肺癌细胞,具有显着的抗肿瘤、抗惊厥和镇静作用。

天然产物

Paederosidic acid
Cat.No: T5739
Synonym: 鸡屎藤苷酸,异戊二酸 紫草酸
Target: Apoptosis, BCL
Cat. No. Product Name Species Expression System
TMPY-04699 GAD65 Protein, Human, Recombinant (GST)

glutamate decarboxylase 2 (pancreatic islets and brain, ...

Human Baculovirus Insect Cells
GAD65 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 92.6 kDa and the accession number is Q05329.
TMPY-01590 GAD65 Protein, Mouse, Recombinant (His & GST)

glutamate decarboxylase 2 (pancreatic islets and brain, ...

Mouse Baculovirus Insect Cells
GAD65 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 93 kDa and the accession number is P48320.
TMPY-03515 GAD65 Protein, Mouse, Recombinant

glutamate decarboxylase 2 (pancreatic islets and brain, ...

Mouse Baculovirus Insect Cells
GAD65 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 65.4 kDa and the accession number is P48320.

重组蛋白

GAD65 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04699
Species: Human
Expression System: Baculovirus Insect Cells
GAD65 Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-01590
Species: Mouse
Expression System: Baculovirus Insect Cells
GAD65 Protein, Mouse, Recombinant
Cat.No: TMPY-03515
Species: Mouse
Expression System: Baculovirus Insect Cells
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