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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T60266 (Rac)-Indoximod

(Rac)-Indoximod (1-Methyl-DL-tryptophan) is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO). Combined treatment with IFN-γ and (Rac)-Indoximod significantly suppresses the activity of α-SMA-expressing human cardiac myofibroblasts (hCMs) and promotes apoptosis by up-regulating the genes IRF-1, Fas, and FasL. Moreover, this co-treatment effectively improves cardiac fibrosis[1].
T6543 Indoximod

NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan,吲哚莫德

Indoleamine 2,3-Dioxygenase (IDO) Metabolism
Indoximod (Indoximod (NLG-8189)) 是一种具有口服具有活力的吲哚胺2,3-双加氧酶(IDO) 途径抑制剂。它在调节 mTOR 中充当 Trp 模拟物。它是一种可用于癌症研究的免疫代谢佐剂。

化合物

(Rac)-Indoximod
Cat.No: T60266
Synonym:
Target:
Indoximod
Cat.No: T6543
Synonym: NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan,吲哚莫德
Target: Indoleamine 2,3-Dioxygenase (IDO)
Cat. No. Product Name Target Signaling Pathways
T4S0290 Araloside A

Chikusetsusaponin IV,竹节参皂苷IV

RAAS; Fas/FasL Apoptosis; Endocrinology/Hormones
Araloside A (Chikusetsusaponin IV) 是竹节参中的一种成分,对肾素renin 具有低抑制活性(IC50:77.4 μM)。
TN4496 Marginatoxin

Caspase; Fas/FasL Apoptosis; Proteases/Proteasome
Marginatoxin may be a promising chemopreventive agent for treating hepatocellular carcinoma, it induces human hepatoma BEL-7402 cells apoptosis in vitro and in vivo via activation of Fas/FasL-mediated apoptotic pathway.
T3S1967 (S)-Indoximod

N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine

Others; Indoleamine 2,3-Dioxygenase (IDO) Metabolism; Others
(S)-Indoximod (L-Abrine) 是一种吲哚胺-2,3-双加氧酶 (IDO) 抑制剂,可用于研究癌症。

天然产物

Araloside A
Cat.No: T4S0290
Synonym: Chikusetsusaponin IV,竹节参皂苷IV
Target: RAAS, Fas/FasL
Marginatoxin
Cat.No: TN4496
Synonym:
Target: Caspase, Fas/FasL
(S)-Indoximod
Cat.No: T3S1967
Synonym: N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine
Target: Others, Indoleamine 2,3-Dioxygenase (IDO)
TargetMol Loading
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