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Cat. No. Product Name Target Signaling Pathways
T7222 GS-441524

GS 441524 triphosphate

Others; SARS-CoV; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
GS-441524 是 Remdesivir 的主要活性代谢物,活性更优于 Remdesivir ,治疗患有自然发生的猫传染性腹膜炎的猫。
T9617 RdRP-IN-2

SARS-CoV Microbiology/Virology
RdRP-IN-2 是一种依赖于 RNA 的 RNA 聚合酶 (RdRp) 抑制剂。它显著抑制 SARS-CoV-2 RdRp,IC50 为 41.2 µM。它还抑制猫冠状病毒 (FIPV) 复制。
T38174 Mpro inhibitor N3 hemihydrate

Mpro inhibitor N3 hemihydrate is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 of 16.77 μM for SARS-CoV-2. Mpro inhibitor N3 hemihydrate specifically inhibits Mpro from multiple coronaviruses, including SARS-CoV and MERS-CoV. Mpro inhibitor N3 hemihydrate displays inhibition against HCoV-229E, FIPV, and MHV-A59 with individual IC50 of 4.0 μM, 8.8 μM, and 2.7 μM, respectively[1][2]. Mpro inhibitor N3 hemihydrate (0-0.64 μM) is able to penetrate cells to inhibit the replication of IBV viruses...
T69657 GS-441524 HCl

GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.78 μM.. GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. GS-441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. GS-441524 was non-toxic in feline cells at concentrations ...

化合物

GS-441524
Cat.No: T7222
Synonym: GS 441524 triphosphate
Target: Others, SARS-CoV, DNA/RNA Synthesis
RdRP-IN-2
Cat.No: T9617
Synonym:
Target: SARS-CoV
Mpro inhibitor N3 hemihydrate
Cat.No: T38174
Synonym:
Target:
GS-441524 HCl
Cat.No: T69657
Synonym:
Target:
TargetMol Loading
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