Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T62391 |
FGFR-IN-6
|
||
FGFR-IN-6 (Compound 5) 是一种 FGFR 抑制剂。 | |||
T2041 |
PD153035
NSC 669364,SU-5271,ZM 252868,AG1517 |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
PD153035 (NSC-669364) 是一种EGFR 抑制剂,Ki 和IC50值分别为6和25 pM。 | |||
T2361 |
LY2874455
LY 2874455,LY-2874455 |
VEGFR; FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
LY2874455 是pan-FGFR 抑制剂,能够抑制FGFR1 (IC50:2.8 nM),FGFR2 (IC50:2.6 nM),FGFR3 (IC50:6.4 nM),FGFR4 (IC50:6 nM)。 | |||
T61660 |
FGFR-IN-3
|
||
FGFR-IN-3 (compound 6) is a highly potent and orally active modulator of FGFR (fibroblast growth factor receptor). It has the ability to penetrate the blood-brain barrier (BBB). Additionally, FGFR-IN-3 exhibits significant neuroprotective properties. Therefore, it holds potential for research on neurodegenerative diseases [1]. | |||
T82405 |
FGFR3-IN-6
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR3-IN-6为FGFR3选择性抑制剂,具有低于350 nM 的IC50,适用于癌症研究领域。 |