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Search Results for " erlotinib 13c6 "

3

抑制剂 & 化合物

3

同位素

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Cat. No.	Product Name	Target	Signaling Pathways
T0373L1	Erlotinib mesylate CP-358774,CP-358,774,埃罗替尼甲磺酸盐,OSI-774,CP358774,OSI 774	Others	Others
	Erlotinib is an epidermal growth factor receptor inhibitor. Erlotinib binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor.
T0373	Erlotinib OSI-744,NSC 718781,CP358774,埃罗替尼,R1415	EGFR; Autophagy	Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Erlotinib (CP358774) 是一种 EGFR 一代抑制剂，抑制 EGFR 19 Del 和 L858R 突变。Erlotinib 具有抗肿瘤活性，用于治疗 EGFR 突变的非小细胞肺癌。Erlotinib 用药会产生 EGFR C797S 耐药突变。
T0373L	Erlotinib hydrochloride 盐酸埃罗替尼,OSI-744,NSC 718781,Erlotinib HCl,CP-358774	EGFR; Autophagy	Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Erlotinib hydrochloride (NSC 718781) 抑制EGFR 激酶的IC50为 2 nM，用于治疗非小细胞肺癌。

化合物

Erlotinib mesylate

Cat.No: T0373L1

Synonym: CP-358774,CP-358,774,埃罗替尼甲磺酸盐,OSI-774,CP358774,OSI 774

Target: Others

Cat.No: T0373

Synonym: OSI-744,NSC 718781,CP358774,埃罗替尼,R1415

Target: EGFR, Autophagy

Erlotinib hydrochloride

Cat.No: T0373L

Synonym: 盐酸埃罗替尼,OSI-744,NSC 718781,Erlotinib HCl,CP-358774

Target: EGFR, Autophagy

Cat. No.	Product Name	Target	Signaling Pathways
T35915	Erlotinib-13C6 Erlotinib-13C6
	Erlotinib-13C6 (CP-358774-13C6) is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1]. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1].Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[2]...
T11229	Erlotinib-d6 OSI-774 D6,NSC 718781 D6,CP-358774 D6	Others	Others
	Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .
T19312	Erlotinib-d6 hydrochloride CP-358774 D6 hydrochloride,NSC 718781 D6 hydrochloride,Erlotinib D6 hydrochloride,OSI-774 D6 hydrochloride	Others	Others
	Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.

同位素

Erlotinib-13C6

Cat.No: T35915

Synonym: Erlotinib-13C6

Cat.No: T11229

Synonym: OSI-774 D6,NSC 718781 D6,CP-358774 D6

Target: Others

Erlotinib-d6 hydrochloride

Cat.No: T19312

Synonym: CP-358774 D6 hydrochloride,NSC 718781 D6 hydrochloride,Erlotinib D6 hydrochloride,OSI-774 D6 hydrochloride

Target: Others

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