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Search Results for " ephb2 "

Targets Recommended: Ephrin Receptor

4

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T67736	ALW-II-49-7	Ephrin Receptor	Tyrosine Kinase/Adaptors
	ALW-II-49-7 是选择性的 EphB2 抑制剂，细胞内 EC50 值为 40 nM。
T80897	UniPR1447	Ephrin Receptor	Tyrosine Kinase/Adaptors
	UniPR1447 是一种双重EphA2和EphB2拮抗剂，其对EphA2−ephrin-A1结合的IC50为6.6 μM。
T2456	Tivozanib 替沃扎尼,AV-951,KRN951	VEGFR; PDGFR; Ephrin Receptor	Angiogenesis; Tyrosine Kinase/Adaptors
	Tivozanib (KRN951) 是一种选择性的 VEGFR 1/2/3抑制剂，它们的 IC50值分别为0.21 nM、0.16 nM、0.24 nM。
T73368	UniPR505	Ephrin Receptor	Tyrosine Kinase/Adaptors
	UniPR505 是一种有效的 EphA2 拮抗剂（IC50：0.95 µM），是一种具有抗血管生成作用的新型 3α-氨基甲酰氧基衍生物。

化合物

Cat.No: T67736

Target: Ephrin Receptor

Cat.No: T80897

Target: Ephrin Receptor

Cat.No: T2456

Synonym: 替沃扎尼,AV-951,KRN951

Target: VEGFR, PDGFR, Ephrin Receptor

Cat.No: T73368

Target: Ephrin Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00424	EphB2 Protein, Human, Recombinant (hFc) EPHB2,Ephrin type-B receptor 2,	Human	HEK293 Cells
	Ephrin type-B receptor 2(EPHB2) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHB2 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphospha...
TMPK-00563	EPHB2 Protein, Cynomolgus, Recombinant (His) DRT,Nuk,Sek3,TYRO5,EPHT3,HEK5,EphB2,Qek	Cynomolgus	HEK293 Cells
	EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.
TMPY-03621	EphB2 Protein, Mouse, Recombinant (hFc) Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,P...	Mouse	HEK293 Cells
	EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPY-04216	EphB2 Protein, Mouse, Recombinant (His) Drt,Nuk,Qek5,Tyro5,Prkm5,Sek3,ETECK,Cek5,Hek5,EPH receptor B...	Mouse	HEK293 Cells
	EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3.
TMPY-01067	EphB2 Protein, Human, Recombinant (His) EPH receptor B2,DRT,EK5,PCBC,ERK,CAPB,EPHT3,Hek5,Ty...	Human	HEK293 Cells
	EphB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P29323-2.
TMPY-00784	EphB2 Protein, Human, Recombinant (His & hFc) Tyro5,EPHT3,DRT,EK5,PCBC,ERK,EPH receptor B2,Hek5,C...	Human	HEK293 Cells
	EphB2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 86 kDa and the accession number is P29323-2.
TMPY-04386	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,...	Human	Baculovirus Insect Cells
	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPY-02191	BLNK Protein, Human, Recombinant (His) BLNK-S,bca,SLP-65,B-cell linker,LY57,SLP65,AGM4,BASH	Human	HEK293 Cells
	B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65 and BLNK, is a cytoplasm and cell membrane protein which contains oneSH2 domain. BLNK is expressed in B-cell lineage and fibroblast cell lines. Highest levels of expression is in the spleen, with lower levels in the liver, kidney, pancreas, small inte...

重组蛋白

EphB2 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00424

Species: Human

Expression System: HEK293 Cells

EPHB2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00563

Species: Cynomolgus

Expression System: HEK293 Cells

EphB2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03621

Species: Mouse

Expression System: HEK293 Cells

EphB2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04216

Species: Mouse

Expression System: HEK293 Cells

EphB2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01067

Species: Human

Expression System: HEK293 Cells

EphB2 Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-00784

Species: Human

Expression System: HEK293 Cells

EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

Cat.No: TMPY-04386

Species: Human

Expression System: Baculovirus Insect Cells

BLNK Protein, Human, Recombinant (His)

Cat.No: TMPY-02191

Species: Human

Expression System: HEK293 Cells

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