Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0216L |
Eletriptan
UK-116,044-04 [as hydrobromide],UNII-22QOO9B8KI,UK-116,044,UK 116044 |
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Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug. | |||
T0216 |
Eletriptan hydrobromide
Eletriptan HBr,UK-116044,依来曲普坦氢溴酸盐 |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Eletriptan hydrobromide (Eletriptan HBr) 是一种口服活性激动剂,对 5-HT1B/1D 受体具有特异性亲和力,Ki 值分别为 0.92 和 3.14 nM。 | |||
T35715 |
N-desmethyl Eletriptan
|
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N-desmethyl Eletriptan is a metabolite of eletriptan .1It is formed from eletriptan primarily by the cytochrome P450 (CYP) isoform CYP3A4 in human liver microsomes. 1.Evans, D.C., O’Connor, D., Lake, B.G., et al.Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoproteinDrug Metab. Dispos.31(7)861-869(2003) |